SCHEMBL25201617

SCHEMBL25201617

O=C(O)COc1ccc(C(=O)/C=C/c2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 7/20 0.75
CYP1B1 Q16678 7/20 0.75
MAOB P27338 6/20 0.75
P4HB P07237 1/20 0.63
KMT2A Q03164 3/20 0.62
MEN1 O00255 2/20 0.62
NPC1 O15118 2/20 0.61
RAB9A P51151 2/20 0.61
POLB P06746 1/20 0.61
BLM P54132 1/20 0.61
GPR35 Q9HC97 1/20 0.61
KEAP1 Q14145 1/20 0.58
NFE2L2 Q16236 1/20 0.58
MAOA P21397 1/20 0.53
MAPT P10636 1/20 0.53
PPARA Q07869 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11459734 0.89 KMT2A (0.75) MAOBKMT2AMEN1NPC1RAB9A
SCHEMBL11459733 0.89 KMT2A (0.75) MAOBKMT2AMEN1NPC1RAB9A
SCHEMBL25207358 0.87 SMN1; SMN2 (0.67) CYP1A1CYP1B1MAOBKMT2AMEN1
SCHEMBL25225655 0.87 SMN1; SMN2 (0.67) CYP1A1CYP1B1MAOBKMT2AMEN1
SCHEMBL25193773 0.86 CYP1A1 (0.74) CYP1A1CYP1B1MAOBP4HBKEAP1
SCHEMBL25200433 0.85 MAOB (0.73) CYP1A1CYP1B1MAOBKMT2AMEN1
SCHEMBL25210712 0.85 MAOB (0.73) CYP1A1CYP1B1MAOBKMT2AMEN1
Cinfenoac SCHEMBL25209635 0.85 KMT2A (0.70) MAOBKMT2AMEN1NPC1RAB9A
SCHEMBL11452467 0.85 KMT2A (0.70) MAOBKMT2AMEN1NPC1RAB9A
Cinfenoac SCHEMBL1516598 0.85 KMT2A (0.70) MAOBKMT2AMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B CYP1A1 696/4885CYP1B1 230/4885MAOB 1004/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 CYP1A1 1747/4885CYP1B1 1027/4885MAOB 2435/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 CYP1A1 1747/4885CYP1B1 1027/4885MAOB 2435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.