Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29263207 | 0.92 | LMNA (0.40) | P2RX7SMN1; SMN2LMNAALDH1A1TSHR | |
| SCHEMBL25228227 | 0.85 | BDKRB1 (0.35) | HSP90AA1HSP90AB1 | |
| SCHEMBL30462396 | 0.85 | CA1 (0.36) | P2RX7SMN1; SMN2LMNAALDH1A1TSHR | |
| SCHEMBL25228631 | 0.85 | CA1 (0.36) | P2RX7SMN1; SMN2LMNAALDH1A1TSHR | |
| SCHEMBL30368503 | 0.83 | MAPT (0.40) | P2RX7SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL30301793 | 0.83 | MAPT (0.40) | P2RX7SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL30301765 | 0.83 | HSP90AA1 (0.46) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL25513324 | 0.82 | MEN1 (0.38) | SMN1; SMN2LMNATSHRL3MBTL1MEN1 | |
| SCHEMBL30301742 | 0.82 | HSP90AA1 (0.45) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL25229325 | 0.82 | SIGMAR1 (0.37) | P2RX7SMN1; SMN2LMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4441040-A1 | INDOLINES AS PROTAC COMPOUNDS | Neophore Limited (GB) | 2024-10-09 | — | — | EP | disclosed |
| WO-2023094833-A1 | INDOLINES AS PROTAC COMPOUNDS | Neophore Limited (GB) | 2023-06-01 | — | — | WO | disclosed |