SCHEMBL25202026

SCHEMBL25202026

COc1ccc(C=CC(=O)c2c(O)cc(O)cc2OC)cc1OC

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 8/20 0.83
MEN1 O00255 5/20 0.74
KMT2A Q03164 5/20 0.74
MAPT P10636 4/20 0.74
KCNA3 P22001 1/20 0.74
NPSR1 Q6W5P4 1/20 0.74
TDP1 Q9NUW8 4/20 0.70
CYP3A4 P08684 3/20 0.70
HPGD P15428 3/20 0.70
KDM4E B2RXH2 2/20 0.70
ALDH1A1 P00352 2/20 0.70
TP53 P04637 2/20 0.70
ALOX15 P16050 2/20 0.70
MAPK1 P28482 2/20 0.70
MCL1 Q07820 1/20 0.70
USP2 O75604 1/20 0.70
ALOX12 P18054 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
NFKB1 P19838 1/20 0.66
DPP4 P27487 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31384903 1.00 ABCG2 (0.83) ABCG2MEN1KMT2AMAPTKCNA3
SCHEMBL30383965 0.94 ABCG2 (0.78) ABCG2MEN1KMT2AMAPTKCNA3
SCHEMBL30384011 0.94 ABCG2 (0.78) ABCG2MEN1KMT2AMAPTKCNA3
SCHEMBL25223566 0.94 ABCG2 (0.78) ABCG2MEN1KMT2AMAPTKCNA3
SCHEMBL25198039 0.94 ABCG2 (0.78) ABCG2MEN1KMT2AMAPTKCNA3
SCHEMBL25190941 0.93 ABCG2 (0.76) ABCG2MEN1KMT2AMAPTKCNA3
SCHEMBL31233058 0.93 ABCG2 (0.76) ABCG2MEN1KMT2AMAPTKCNA3
SCHEMBL25194231 0.93 ABCG2 (0.76) ABCG2MEN1KMT2AMAPTKCNA3
SCHEMBL1938672 0.92 MEN1 (0.83) ABCG2MEN1KMT2AMAPTKCNA3
SCHEMBL1938668 0.92 MEN1 (0.83) ABCG2MEN1KMT2AMAPTKCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCG2 1606/4885MEN1 3367/4885KMT2A 2792/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MEN1 2457/4885KMT2A 3188/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MEN1 2457/4885KMT2A 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.