SCHEMBL25202035

SCHEMBL25202035

NC(=O)N1CCN(c2ccc(C(=O)/C=C/c3ccc(/C=C/C(=O)O)cc3)cc2)CC1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 3/20 0.59
▸ CTSB P07858 3/20 0.59
▸ MAPT P10636 5/20 0.57
▸ MAOB P27338 3/20 0.57
▸ SMN1; SMN2 Q16637 2/20 0.57
▸ L3MBTL1 Q9Y468 2/20 0.57
▸ NPC1 O15118 2/20 0.57
▸ RAB9A P51151 2/20 0.57
▸ MEN1 O00255 1/20 0.57
▸ ALDH1A1 P00352 1/20 0.57
▸ KMT2A Q03164 1/20 0.57
▸ HDAC3 O15379 3/20 0.57
▸ HDAC4 P56524 3/20 0.57
▸ HDAC1 Q13547 3/20 0.57
▸ HDAC7 Q8WUI4 3/20 0.57
▸ HDAC2 Q92769 3/20 0.57
▸ HDAC10 Q969S8 3/20 0.57
▸ HDAC11 Q96DB2 3/20 0.57
▸ HDAC8 Q9BY41 3/20 0.57
▸ HDAC6 Q9UBN7 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31233211 1.00 CTSL (0.59) CTSLCTSBMAPTMAOBSMN1; SMN2
SCHEMBL25214874 1.00 CTSL (0.59) CTSLCTSBMAPTMAOBSMN1; SMN2
Hydrochloric Acid SCHEMBL4359025 0.99 CTSL (0.57) CTSLCTSBMAPTMAOBSMN1; SMN2
Hydrochloric Acid SCHEMBL1482158 0.99 CTSL (0.57) CTSLCTSBMAPTMAOBSMN1; SMN2
Hydrochloric Acid SCHEMBL1482160 0.99 CTSL (0.57) CTSLCTSBMAPTMAOBSMN1; SMN2
SCHEMBL27894889 0.90 CTSL (0.61) CTSLCTSBMAPTMAOBSMN1; SMN2
SCHEMBL1482489 0.89 HDAC3 (0.73) CTSLCTSBMAPTMAOBSMN1; SMN2
SCHEMBL1482492 0.89 HDAC3 (0.73) CTSLCTSBMAPTMAOBSMN1; SMN2
SCHEMBL27741235 0.88 CTSL (0.54) CTSLCTSBMAPTMAOBSMN1; SMN2
SCHEMBL1481814 0.87 HDAC3 (0.60) CTSLCTSBMAPTMAOBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B CTSL 357/4885CTSB 51/4885MAPT 3297/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 CTSL 310/4885CTSB 60/4885MAPT 3512/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 CTSL 310/4885CTSB 60/4885MAPT 3512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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