SCHEMBL25202039

SCHEMBL25202039

COc1ccc(/C=C\C(=O)c2ccccc2C(=O)O)cc1OC

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 8/20 0.76
MAOB P27338 2/20 0.76
ACHE P22303 1/20 0.76
MEN1 O00255 5/20 0.67
KMT2A Q03164 5/20 0.67
ALDH1A1 P00352 4/20 0.67
HPGD P15428 4/20 0.67
SMN1; SMN2 Q16637 4/20 0.67
TP53 P04637 3/20 0.67
CYP3A4 P08684 3/20 0.67
MAPK1 P28482 3/20 0.67
HIF1A Q16665 2/20 0.67
PDE4D Q08499 2/20 0.67
HSD17B10 Q99714 2/20 0.67
KDM4E B2RXH2 2/20 0.67
PTGS2 P35354 2/20 0.67
ALOX12 P18054 2/20 0.67
CYP1A2 P05177 1/20 0.67
CYP2C9 P11712 1/20 0.67
CYP2C19 P33261 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2944206 1.00 ABCG2 (0.76) ABCG2MAOBACHEMEN1KMT2A
SCHEMBL2944203 1.00 ABCG2 (0.76) ABCG2MAOBACHEMEN1KMT2A
SCHEMBL30383263 1.00 ABCG2 (0.76) ABCG2MAOBACHEMEN1KMT2A
SCHEMBL25196951 0.90 ABCG2 (0.62) ABCG2MAOBACHEMEN1KMT2A
SCHEMBL19695924 0.89 ABCG2 (0.61) ABCG2MAOBACHEMEN1KMT2A
SCHEMBL25285114 0.89 ABCG2 (0.61) ABCG2MAOBACHEMEN1KMT2A
SCHEMBL30382797 0.89 ABCG2 (0.61) ABCG2MAOBACHEMEN1KMT2A
SCHEMBL16740656 0.89 ABCG2 (0.80) ABCG2MAOBACHEMEN1KMT2A
SCHEMBL16740655 0.89 ABCG2 (0.80) ABCG2MAOBACHEMEN1KMT2A
SCHEMBL27907246 0.88 ABCG2 (0.74) ABCG2MAOBACHEMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCG2 1606/4885MAOB 1004/4885ACHE 806/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MAOB 2435/4885ACHE 656/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MAOB 2435/4885ACHE 656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.