SCHEMBL25202277

SCHEMBL25202277

O=C(O)CCOc1ccc(C=CC(=O)c2ccccc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.70
▸ NPC1 O15118 1/20 0.70
▸ RAB9A P51151 1/20 0.70
▸ KMT2A Q03164 1/20 0.70
▸ BCHE P06276 10/20 0.62
▸ CYP3A4 P08684 1/20 0.62
▸ NFKB1 P19838 1/20 0.62
▸ NFKB2 Q00653 1/20 0.62
▸ RELA Q04206 1/20 0.62
▸ ACHE P22303 9/20 0.62
▸ MAOB P27338 2/20 0.62
▸ MAOA P21397 1/20 0.62
▸ PPARA Q07869 2/20 0.61
▸ ABCG2 Q9UNQ0 1/20 0.60
▸ PLIN1 O60240 1/20 0.58
▸ LMNA P02545 1/20 0.58
▸ TNFRSF1A P19438 1/20 0.58
▸ RECQL P46063 1/20 0.58
▸ PLIN5 Q00G26 1/20 0.58
▸ CYP1B1 Q16678 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2993225 0.91 PPARA (0.72) MAPTNPC1RAB9AKMT2ABCHE
SCHEMBL2993228 0.91 PPARA (0.72) MAPTNPC1RAB9AKMT2ABCHE
SCHEMBL13207452 0.90 MAPT (0.76) MAPTNPC1RAB9AKMT2ABCHE
SCHEMBL25208789 0.88 MAOB (0.70) MAPTNPC1RAB9AKMT2ABCHE
SCHEMBL25188984 0.88 MAOB (0.71) MAPTNPC1RAB9AKMT2ABCHE
SCHEMBL25197151 0.88 MAOB (0.70) MAPTNPC1RAB9AKMT2ABCHE
SCHEMBL25190838 0.88 MAOB (0.70) MAPTNPC1RAB9AKMT2ABCHE
SCHEMBL25193934 0.88 MAOB (0.73) MAPTNPC1RAB9AKMT2AMAOB
SCHEMBL25193715 0.87 BCHE (0.70) BCHEACHEMAOBMAOAPPARA
SCHEMBL25189021 0.87 MAPT (0.72) MAPTNPC1RAB9AKMT2ABCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885NPC1 1378/4885RAB9A 480/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885NPC1 1908/4885RAB9A 1327/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885NPC1 1908/4885RAB9A 1327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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