SCHEMBL2520629

SCHEMBL2520629

CCCOOC(=O)C1CCCCC1.O=C([O-])C1CCCCC1.O=C([O-])C1CCCCC1.[Zr+2]

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
NAAA Q02083 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PPM1B O75688 1/20 0.32
PTPN1 P18031 1/20 0.32
PPP1CC P36873 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
POLB P06746 1/20 0.31
HSD11B1 P28845 1/20 0.31
ADH1A P07327 1/20 0.30
ADRB2 P07550 1/20 0.30
ADRB1 P08588 1/20 0.30
ADRB3 P13945 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2515136 0.91 NAAA (0.38) ALDH1A1NAAASMN1; SMN2MEN1KMT2A
SCHEMBL2523174 0.89 ALDH1A1 (0.41) ALDH1A1NAAASMN1; SMN2PPM1BPTPN1
SCHEMBL1131547 0.80 NAAA (0.44) ALDH1A1NAAASMN1; SMN2MEN1KMT2A
SCHEMBL2518599 0.79 NAAA (0.42) ALDH1A1NAAASMN1; SMN2MEN1KMT2A
SCHEMBL28656830 0.78 NAAA (0.49) ALDH1A1NAAACES2
SCHEMBL28701719 0.76 ALDH1A1 (0.49) ALDH1A1NAAASMN1; SMN2MEN1KMT2A
SCHEMBL11969563 0.74 SMN1; SMN2 (0.35) ALDH1A1SMN1; SMN2MEN1KMT2ACES2
SCHEMBL20960095 0.72 MAPT (0.38) ALDH1A1SMN1; SMN2PPM1BPTPN1PPP1CC
SCHEMBL29116791 0.72 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2MEN1KMT2ACES2
SCHEMBL148328 0.72 ALDH1A1 (0.53) ALDH1A1NAAASMN1; SMN2PPM1BPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9051435-B2 Silanol condensation catalyst, heat-curable silicone resin composition for sealing photosemiconductors and sealed photosemiconductor using same THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-06-09 US disclosed
US-20140256539-A1 SILANOL CONDENSATION CATALYST, HEAT-CURABLE SILICONE RESIN COMPOSITION FOR SEALING PHOTOSEMICONDUCTORS AND SEALED PHOTOSEMICONDUCTOR USING SAME THE YOKOHAMA RUBBER CO., LTD. (JP) 2014-09-11 US disclosed
US-8772431-B2 Silanol condensation catalyst, heat-curable silicone resin composition for sealing photosemiconductors and sealed photosemiconductor using same THE YOKOHAMA RUBBER CO., LTD. (JP) 2014-07-08 US disclosed
US-20110248314-A1 SILANOL CONDENSATION CATALYST, HEAT-CURABLE SILICONE RESIN COMPOSITION FOR SEALING PHOTOSEMICONDUCTORS AND SEALED PHOTOSEMICONDUCTOR USING SAME THE YOKOHAMA RUBBER CO., LTD. (JP) 2011-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110248314-A1 SILANOL CONDENSATION CATALYST, HEAT-CURABLE SILICONE RESIN COMPOSITION FOR SEALING PHOTOSEMICONDUCTORS AND SEALED PHOTOSEMICONDUCTOR USING SAME ASH2L, RCOR1, SEM1 ALDH1A1 1732/4885NAAA 4190/4885SMN1; SMN2 3472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.