SCHEMBL25206604

SCHEMBL25206604

CCCN(C(=O)c1cc(-c2cnn(-c3ccccc3)c2)cs1)[C@@H]1CCNC1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 15/20 0.46
SLC6A2 P23975 15/20 0.46
SLC6A3 Q01959 11/20 0.46
KCNH2 Q12809 5/20 0.41
MBTPS1 Q14703 2/20 0.38
CACNA2D1 P54289 2/20 0.37
CYP2D6 P10635 3/20 0.37
CHRM3 P20309 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25243811 1.00 SLC6A4 (0.46) SLC6A4SLC6A2SLC6A3KCNH2MBTPS1
SCHEMBL25233602 1.00 SLC6A4 (0.46) SLC6A4SLC6A2SLC6A3KCNH2MBTPS1
SCHEMBL25225394 0.86 SLC6A4 (0.46) SLC6A4SLC6A2SLC6A3KCNH2MBTPS1
SCHEMBL25225150 0.86 SLC6A4 (0.46) SLC6A4SLC6A2SLC6A3KCNH2MBTPS1
SCHEMBL25204401 0.86 SLC6A4 (0.46) SLC6A4SLC6A2SLC6A3KCNH2MBTPS1
SCHEMBL25205174 0.84 SLC6A4 (0.46) SLC6A4SLC6A2SLC6A3KCNH2MBTPS1
SCHEMBL25236812 0.84 SLC6A4 (0.46) SLC6A4SLC6A2SLC6A3KCNH2MBTPS1
SCHEMBL25509190 0.84 SLC6A4 (0.46) SLC6A4SLC6A2SLC6A3KCNH2MBTPS1
SCHEMBL25215536 0.84 SLC6A4 (0.46) SLC6A4SLC6A2SLC6A3KCNH2MBTPS1
SCHEMBL25230282 0.84 SLC6A4 (0.47) SLC6A4SLC6A2SLC6A3KCNH2MBTPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250049776-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF, IN PARTICULAR FOR A SYSTEMIC TREATMENT OF DISEASES AND CONDITIONS INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM) (FR) 2025-02-13 US disclosed
EP-4183449-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2023-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250049776-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF, IN PARTICULAR FOR A SYSTEMIC TREATMENT OF DISEASES AND CONDITIONS BECN1, TFEB, SQSTM1 SLC6A4 982/4885SLC6A2 884/4885SLC6A3 792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.