Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 10/20 | 0.37 |
| ▸ | ALPL | P05186 | 2/20 | 0.37 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27815378 | 0.98 | CYP3A4 (0.41) | CYP3A4CYP2C9CYP2C19CYP2E1CYP2A6 | |
| Bromide SCHEMBL28926580 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL28156706 | 0.89 | — | — | |
| SCHEMBL28296899 | 0.84 | ALPL (0.39) | CYP3A4CYP2C9CYP2C19QPCTALPL | |
| Ammonia Solution, Strong SCHEMBL28248677 | 0.82 | ALPL (0.38) | CYP3A4CYP2C9CYP2C19QPCTALPL | |
| SCHEMBL27953432 | 0.81 | QPCT (0.42) | CYP3A4CYP2C9CYP2C19QPCTALPL | |
| Phosphoric Acid SCHEMBL3326759 | 0.80 | ALPL (0.42) | CYP3A4CYP2C9CYP2C19CYP2E1CYP2A6 | |
| Phosphoric Acid SCHEMBL3326768 | 0.80 | ALPL (0.42) | CYP3A4CYP2C9CYP2C19CYP2E1CYP2A6 | |
| SCHEMBL27639473 | 0.79 | CYP3A4 (0.38) | CYP3A4CYP2C9CYP2C19CYP2E1CYP2A6 | |
| SCHEMBL27639294 | 0.77 | CYP3A4 (0.37) | CYP3A4CYP2C9CYP2C19CYP2E1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119452083-A | (S) -engineered glycolonitrile aldolase polypeptides and uses thereof | 诺华股份有限公司 | 2025-02-14 | — | — | CN | claimed |
| US-20250188502-A1 | BIOCATALYST AND METHOD FOR THE SYNTHESIS OF UBROGEPANT INTERMEDIATES | ENZYMASTER (NINGBO) BIO-ENGINEERING CO., LTD. (CN) | 2025-06-12 | — | — | US | disclosed |
| CN-119452083-A | (S) -engineered glycolonitrile aldolase polypeptides and uses thereof | 诺华股份有限公司 | 2025-02-14 | — | — | CN | disclosed |
| US-20250043323-A1 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF PREGABALIN INTERMEDIATES | Enzymaster (Ningbo) Bio-Engineering Co., Ltd (CN) | 2025-02-06 | — | — | US | disclosed |
| EP-4490281-A1 | BIOCATALYST AND METHOD FOR THE SYNTHESIS OF UBROGEPANT INTERMEDIATES | Enzymaster (Ningbo) Bio-Engineering Co., Ltd. (CN) | 2025-01-15 | — | — | EP | disclosed |
| EP-4433602-A1 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF PREGABALIN INTERMEDIATES | Enzymaster (Ningbo) Bio-Engineering Co., Ltd. (CN) | 2024-09-25 | — | — | EP | disclosed |
| CN-117425732-A | Biocatalysts and methods for synthesizing pregabalin intermediates | 宁波酶赛生物工程有限公司 | 2024-01-19 | — | — | CN | disclosed |
| CN-117425728-A | Biocatalysts and methods for synthesizing a Ubbelopam intermediate | 宁波酶赛生物工程有限公司 | 2024-01-19 | — | — | CN | disclosed |
| WO-2023185184-A1 | MONOAMINE OXIDASE AND APPLICATION THEREOF | 青岛清原化合物有限公司 | 2023-10-05 | — | — | WO | disclosed |
| WO-2023169071-A1 | MONOAMINE OXIDASE AND USE THEREOF | 青岛清原化合物有限公司 | 2023-09-14 | — | — | WO | disclosed |
| CN-110088079-A | Novel method for early sakabutril intermediate | 诺华股份有限公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-109863162-A | Engineered imine reductases and methods for reductive amination of ketone and amine compounds | 科德克希思公司 | 2019-06-07 | — | — | CN | disclosed |
| CN-109715182-A | It is engineered β-glucosyl enzym and glucosylation method | 科德克希思公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-109715817-A | Hydroxylated biocatalyst and method for compound | 科德克希思公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-108602785-A | Novel process and intermediates | 诺华股份有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-107699548-A | Hydroxylated biocatalyst and method for compound | 科德克希思公司 | 2018-02-16 | — | — | CN | disclosed |
| CN-104428412-B | Biocatalysts and methods for hydroxylation of chemical compounds | 科德克希思公司 | 2017-09-08 | — | — | CN | disclosed |
| CN-104185634-B | Chemical process for preparing spiroindolones and intermediates thereof | 诺华股份有限公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-106479990-A | For preparing the biocatalyzer of the carbamate of hydroxyl replacement | 科德克希思公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-104053771-B | Biocatalysts for the preparation of hydroxy-substituted carbamates | 科德克希思公司 | 2016-11-09 | — | — | CN | disclosed |