Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.42 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.35 |
| ▸ | QPCT | Q16769 | 6/20 | 0.34 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL3326759 | 1.00 | ALPL (0.42) | ALPLPLAAALPGCYP3A4CYP2C9 | |
| Bromide SCHEMBL28926580 | 0.86 | — | — | |
| SCHEMBL25210345 | 0.80 | CYP3A4 (0.42) | ALPLPLAAALPGCYP3A4CYP2C9 | |
| SCHEMBL28452300 | 0.75 | FDPS (0.54) | ALPLPLAAALPGFDPS | |
| SCHEMBL12018590 | 0.74 | ALPL (0.40) | ALPLPLAAALPGQPCTKMT2A | |
| SCHEMBL10529956 | 0.73 | — | — | |
| Phosphoric Acid SCHEMBL28561554 | 0.69 | CPA1 (0.37) | CPB2FDPS | |
| SCHEMBL634200 | 0.68 | CYP1A2 (0.45) | ALPLPLAACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30691991 | 0.68 | CYP2E1 (0.43) | ALPLPLAACYP3A4CYP2C9CYP2C19 | |
| Acetic Acid SCHEMBL29204930 | 0.68 | CPB2 (0.47) | ALPLPLAAALPGCPB2QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394181-B2 | Selectively permeable material, method for producing selectively permeable membrane structure, selectively permeable membrane structure, and air conditioning system | SHIN-ETSU POLYMER CO., LTD. (JP) | 2013-03-12 | — | — | US | disclosed |
| US-20100132559-A1 | SELECTIVELY PERMEABLE MATERIAL, METHOD FOR PRODUCING SELECTIVELY PERMEABLE MEMBRANE STRUCTURE, SELECTIVELY PERMEABLE MEMBRANE STRUCTURE, AND AIR CONDITIONING SYSTEM | SHIN-ETSU POLYMER CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| EP-2098281-A1 | SELECTIVELY PERMEABLE MATERIAL, METHOD FOR PRODUCING SELECTIVELY PERMEABLE MEMBRANE STRUCTURE, SELECTIVELY PERMEABLE MEMBRANE STRUCTURE, AND AIR CONDITIONING SYSTEM | Shin-Etsu Polymer Co. Ltd. (JP) | 2009-09-09 | — | — | EP | disclosed |