Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22659666 | 0.86 | KDM1A (0.39) | P2RX7NPC1RAB9AEPHX2NR1H4 | |
| SCHEMBL3559618 | 0.85 | CHRM4 (0.42) | P2RX7RAB9AERCC1ERCC4EPHX2 | |
| SCHEMBL19212131 | 0.83 | HDAC1 (0.36) | FPR3FPR2NPC1RAB9A | |
| SCHEMBL27150864 | 0.81 | CYP1A2 (0.33) | FPR3FPR2P2RX7AKR1B1RAB9A | |
| SCHEMBL2965399 | 0.77 | AKR1B1 (0.55) | FPR3FPR2P2RX7AKR1B1EPHX2 | |
| SCHEMBL2526148 | 0.77 | SETDB1 (0.43) | P2RX7AKR1B1NPC1RAB9ATTR | |
| SCHEMBL25574990 | 0.77 | AAK1 (0.49) | FPR3FPR2 | |
| SCHEMBL3568253 | 0.76 | P2RX7 (0.53) | P2RX7AKR1B1EPHX2NR1H4AKR1A1 | |
| SCHEMBL31706249 | 0.76 | PTPN7 (0.36) | P2RX7EPHX2 | |
| SCHEMBL7466464 | 0.76 | CXCL8 (0.39) | AKR1B1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086521-A1 | BTK INHIBITORS | BIOGEN MA INC. (US) | 2023-05-19 | — | — | WO | disclosed |