SCHEMBL25210464

SCHEMBL25210464

COc1ccc(C=CC(=O)c2ccc(C(=O)C=Cc3ccc(O)cc3)cc2)cc1O

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSL P07711 2/20 0.74
TUBB4A P04350 1/20 0.71
TUBB P07437 1/20 0.71
TUBA3C P0DPH7 1/20 0.71
TUBA1B P68363 1/20 0.71
TUBA4A P68366 1/20 0.71
TUBB4B P68371 1/20 0.71
TUBB3 Q13509 1/20 0.71
TUBB2A Q13885 1/20 0.71
TUBB8 Q3ZCM7 1/20 0.71
TUBA3E Q6PEY2 1/20 0.71
TUBA1A Q71U36 1/20 0.71
TUBA1C Q9BQE3 1/20 0.71
TUBB6 Q9BUF5 1/20 0.71
TUBB2B Q9BVA1 1/20 0.71
TUBB1 Q9H4B7 1/20 0.71
CALM1 P0DP23 2/20 0.70
MEN1 O00255 4/20 0.69
KMT2A Q03164 4/20 0.69
ABCG2 Q9UNQ0 2/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30383389 1.00 CTSL (0.74) CTSLTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL30266667 0.99 CTSL (0.76) CTSLTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL25184983 0.99 CTSL (0.76) CTSLTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL25197210 0.99 CTSL (0.76) CTSLTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL30383942 0.99 CTSL (0.76) CTSLTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL25196076 0.94 TUBB1 (0.79) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL30384079 0.94 TUBB1 (0.79) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL25196870 0.89 CXCL12 (0.80) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL25221438 0.89 TUBB1 (0.71) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL25230917 0.89 CXCL12 (0.80) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B CTSL 357/4885TUBB4A 3280/4885TUBB 2775/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 CTSL 310/4885TUBB4A 2584/4885TUBB 2272/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 CTSL 310/4885TUBB4A 2584/4885TUBB 2272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.