Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12133415 | 0.91 | MMP14 (0.38) | MMP14KDRALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL31158285 | 0.87 | MMP14 (0.55) | MMP14KDRALDH1A1CYP1A2LMNA | |
| SCHEMBL25717405 | 0.87 | MMP14 (0.46) | MMP14KDRALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL31672215 | 0.87 | MMP14 (0.55) | MMP14KDRALDH1A1CYP1A2LMNA | |
| SCHEMBL1995946 | 0.87 | MMP14 (0.55) | MMP14KDRALDH1A1CYP1A2LMNA | |
| SCHEMBL12134558 | 0.87 | MMP14 (0.55) | MMP14KDRALDH1A1CYP1A2LMNA | |
| SCHEMBL31158287 | 0.87 | MMP14 (0.55) | MMP14KDRALDH1A1CYP1A2LMNA | |
| SCHEMBL25712980 | 0.85 | MMP14 (0.44) | MMP14KDRALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL20588507 | 0.84 | MMP14 (0.54) | MMP14ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL16908127 | 0.83 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP2D6LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023100158-A9 | SUBSTRATES FOR IMAGING GLUCOCEREBROSIDASE ACTIVITY | SIMON FRASER UNIVERSITY (CA) | 2023-12-07 | — | — | WO | claimed |
| WO-2023100158-A1 | SUBSTRATES FOR IMAGING GLUCOCEREBROSIDASE ACTIVITY | SIMON FRASER UNIVERSITY (CA) | 2023-06-08 | — | — | WO | claimed |
| WO-2023100158-A9 | SUBSTRATES FOR IMAGING GLUCOCEREBROSIDASE ACTIVITY | SIMON FRASER UNIVERSITY (CA) | 2023-12-07 | — | — | WO | disclosed |
| WO-2023100158-A1 | SUBSTRATES FOR IMAGING GLUCOCEREBROSIDASE ACTIVITY | SIMON FRASER UNIVERSITY (CA) | 2023-06-08 | — | — | WO | disclosed |