Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 4/20 | 0.44 |
| ▸ | CCNK | O75909 | 4/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.44 |
| ▸ | CDK2 | P24941 | 4/20 | 0.44 |
| ▸ | CDK9 | P50750 | 4/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | CDK7 | P50613 | 2/20 | 0.33 |
| ▸ | CCNH | P51946 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25028896 | 0.91 | GSK3B (0.45) | CCNT1CCNKCCNE1CDK2CDK9 | |
| Trifluoroacetic Acid SCHEMBL29361361 | 0.82 | CCNT1 (0.48) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL25028898 | 0.82 | CCNK (0.40) | CCNT1CCNKCCNE1CDK2CDK9 | |
| Trifluoroacetic Acid SCHEMBL29361498 | 0.81 | CCNT1 (0.42) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL29363980 | 0.79 | CCNT1 (0.49) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL25029216 | 0.79 | CCNT1 (0.49) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL29364398 | 0.79 | SLC6A4 (0.49) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL25029229 | 0.79 | SLC6A4 (0.49) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL25029296 | 0.77 | GSK3B (0.41) | GSK3BDYRK1ANFATC1TBK1CDK7 | |
| SCHEMBL29363610 | 0.77 | GSK3B (0.41) | GSK3BDYRK1ANFATC1TBK1CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |