Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254075 | 0.83 | CES2 (0.58) | POLBHPGDTSHRCES2CES1 | |
| SCHEMBL255022 | 0.83 | POLB (0.67) | POLBHPGDTSHRCES2CES1 | |
| SCHEMBL29482203 | 0.83 | POLB (0.67) | POLBHPGDTSHRCES2CES1 | |
| SCHEMBL7654141 | 0.82 | POLB (0.65) | POLBHPGDTSHRCES2CES1 | |
| SCHEMBL9782204 | 0.81 | POLB (0.59) | POLBHPGDTSHRCES2CES1 | |
| SCHEMBL11455792 | 0.81 | POLB (0.59) | POLBHPGDTSHRCES2CES1 | |
| SCHEMBL11375658 | 0.80 | POLB (0.58) | POLBHPGDTSHRCES2CES1 | |
| SCHEMBL28195080 | 0.80 | CES2 (0.54) | POLBHPGDTSHRCES2CES1 | |
| SCHEMBL27807210 | 0.79 | TP53 (0.61) | POLBHPGDTSHRCES2CES1 | |
| SCHEMBL11212458 | 0.78 | POLB (0.61) | POLBHPGDTSHRCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |