Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29482203 | 0.85 | POLB (0.67) | POLBCES2CES1HPGDTSHR | |
| SCHEMBL255022 | 0.85 | POLB (0.67) | POLBCES2CES1HPGDTSHR | |
| SCHEMBL3280428 | 0.84 | TP53 (0.50) | POLBHPGDTSHRTP53ALDH1A1 | |
| SCHEMBL25211575 | 0.82 | POLB (0.62) | POLBCES2CES1HPGDTSHR | |
| SCHEMBL28448095 | 0.81 | CES2 (0.58) | POLBCES2CES1HPGDTSHR | |
| SCHEMBL11212458 | 0.80 | POLB (0.61) | POLBCES2CES1HPGDTSHR | |
| SCHEMBL3455835 | 0.79 | POLB (1.00) | POLBCES2CES1HPGDTSHR | |
| SCHEMBL9782204 | 0.79 | POLB (0.59) | POLBCES2CES1HPGDTSHR | |
| SCHEMBL20812519 | 0.79 | POLB (0.59) | POLBCES2CES1HPGDTSHR | |
| SCHEMBL11455792 | 0.79 | POLB (0.59) | POLBCES2CES1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489490-B1 | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-03 | — | — | US | disclosed |