SCHEMBL25212950

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30859137	0.90	MAPT (0.55)	SYKIDO1LMNASMN1; SMN2MAPT
	SCHEMBL4181948	0.86	SYK (0.57)	SYKIDO1LMNASMN1; SMN2MAPT
	SCHEMBL15202883	0.85	SYK (0.64)	SYKIDO1LMNASMN1; SMN2MAPT
	SCHEMBL6390091	0.83	ALDH1A1 (0.49)	LMNASMN1; SMN2MAPTHTTMAPK1
	SCHEMBL13938297	0.82	HTT (0.65)	SYKIDO1LMNASMN1; SMN2MAPT
	SCHEMBL13480435	0.82	MAPT (0.65)	SYKIDO1LMNASMN1; SMN2MAPT
	SCHEMBL25243786	0.82	SYK (0.42)	SYKIDO1MAPTHTTL3MBTL1
	SCHEMBL31300270	0.82	MAPT (0.52)	SYKIDO1LMNASMN1; SMN2MAPT
	SCHEMBL3955009	0.81	SYK (0.57)	SYKIDO1LMNASMN1; SMN2MAPT
	SCHEMBL15679441	0.81	MAPT (0.64)	SYKIDO1LMNASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.