Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25223211 | 0.90 | POLB (0.53) | POLBKMT2ACYP19A1ALDH1A1AHR | |
| SCHEMBL25212820 | 0.86 | CYP19A1 (0.59) | POLBCYP19A1ALDH1A1AHRMAPT | |
| SCHEMBL25241055 | 0.85 | HSD11B1 (0.50) | POLBKMT2ACYP19A1NFATC1SMN1; SMN2 | |
| SCHEMBL25247977 | 0.85 | CYP19A1 (0.52) | POLBCYP19A1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL25215953 | 0.82 | NFATC1 (0.46) | CYP19A1ALDH1A1NFATC1AHRMAPT | |
| SCHEMBL25214430 | 0.81 | CYP19A1 (0.68) | POLBKMT2ACYP19A1MAPT | |
| SCHEMBL25214473 | 0.81 | IDO1 (0.50) | POLBKMT2AALDH1A1MAPTCNR1 | |
| SCHEMBL25208727 | 0.79 | FEN1 (0.48) | CYP19A1NFATC1CNR1KDM1AMAOA | |
| SCHEMBL25270169 | 0.79 | ALDH1A1 (0.69) | KMT2ACYP19A1ALDH1A1MAPTCNR1 | |
| SCHEMBL25250699 | 0.79 | CYP19A1 (0.59) | POLBKMT2ACYP19A1ALDH1A1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250093329-A1 | SCREENING OF COMPOUNDS | THE UNIVERSITY OF TULSA | 2025-03-20 | — | — | US | disclosed |
| EP-4469592-A1 | SCREENING OF COMPOUNDS | The University Of Tulsa (US) | 2024-12-04 | — | — | EP | disclosed |
| US-20230266302-A1 | SYNTHESIS AND USE OF N-BENZYL SULFONAMIDES | THE UNIV OF TULSA (US) | 2023-08-24 | — | — | US | disclosed |
| WO-2023146904-A1 | SCREENING OF COMPOUNDS | THE UNIVERSITY OF TULSA (US) | 2023-08-03 | — | — | WO | disclosed |
| EP-4185706-A1 | SYNTHESIS AND USE OF N-BENZYL SULFONAMIDES | The University Of Tulsa (US) | 2023-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230266302-A1 | SYNTHESIS AND USE OF N-BENZYL SULFONAMIDES | ATP5ME, ATP5F1B, ATP5MG | POLB 702/4885KMT2A 1813/4885CYP19A1 1206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.