SCHEMBL25213345

SCHEMBL25213345

CCC(C)(C)OP(Cl)Oc1ccccc1C

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.33
GLA P06280 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
MEN1 O00255 1/20 0.33
TSHR P16473 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 2/20 0.32
KDM4E B2RXH2 3/20 0.32
CYP1A2 P05177 1/20 0.32
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31
CRHBP P24387 1/20 0.31
CRHR2 Q13324 1/20 0.31
ADRB2 P07550 1/20 0.31
ADRB1 P08588 1/20 0.31
ADRB3 P13945 1/20 0.31
SCN4A P35499 1/20 0.31
TDP1 Q9NUW8 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25226070 0.83 TSHR (0.36) ALDH1A1GLASMN1; SMN2NPC1RAB9A
SCHEMBL3128896 0.78 TSHR (0.43) ALDH1A1GLASMN1; SMN2NPC1RAB9A
SCHEMBL25212980 0.78 LTA4H (0.32) CYP1A2
SCHEMBL25199054 0.76 TDP1 (0.36) ALDH1A1GLASMN1; SMN2NPC1RAB9A
SCHEMBL25195694 0.74 NPC1 (0.37) ALDH1A1GLASMN1; SMN2NPC1RAB9A
SCHEMBL17929073 0.73 TSHR (0.39) ALDH1A1GLASMN1; SMN2NPC1RAB9A
SCHEMBL25199792 0.73 TSHR (0.39) ALDH1A1GLASMN1; SMN2NPC1RAB9A
SCHEMBL15759300 0.73 TSHR (0.42) ALDH1A1GLASMN1; SMN2NPC1RAB9A
SCHEMBL25214560 0.72 CYP1A2 (0.39) ALDH1A1GLASMN1; SMN2NPC1RAB9A
SCHEMBL25199999 0.72 ACHE (0.41) ALDH1A1SMN1; SMN2RAB9AMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US claimed
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US disclosed