SCHEMBL2521337

SCHEMBL2521337

C=COCc1ccc(C=C)cc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34
HDAC8 Q9BY41 1/20 0.33
POLB P06746 1/20 0.31
TRPA1 O75762 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5479582 0.88 IDO1 (0.35) ALDH1A1TSHR
Styrene SCHEMBL11234469 0.85 ALDH1A1 (0.56) ALDH1A1TSHRHIF1A
SCHEMBL23731306 0.83 ALDH1A1 (0.46) ALDH1A1TSHRTDP1CHRNB2CHRNB4
SCHEMBL16690572 0.82 ALDH1A1 (0.41) ALDH1A1TSHRCHRNB2CHRNB4CHRNA3
SCHEMBL91631 0.82 ALDH1A1 (0.50) ALDH1A1TSHRTDP1CHRNB2CHRNB4
SCHEMBL5066935 0.81 ALDH1A1 (0.55) ALDH1A1TSHRTDP1CHRNB2CHRNB4
SCHEMBL10339592 0.79 ALDH1A1 (0.42) ALDH1A1TSHRTDP1CHRNB2CHRNB4
SCHEMBL20459831 0.79 ALDH1A1 (0.38) ALDH1A1TSHRTDP1CHRNB2CHRNB4
SCHEMBL14076881 0.79 ALDH1A1 (0.38) ALDH1A1TSHRTDP1CHRNB2CHRNB4
SCHEMBL896480 0.79 ALDH1A1 (0.30) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8334338-B2 Composition for forming resist lower layer film JSR CORPORATION (JP) 2012-12-18 US disclosed
US-20110251323-A1 COMPOSITION FOR FORMING RESIST LOWER LAYER FILM JSR CORPORATION 2011-10-13 US disclosed
EP-1386904-B1 Acenaphthylene derivative, polymer, and antireflection film-forming composition JSR CORP (JP) 2008-09-17 EP disclosed
US-7037994-B2 Acenaphthylene derivative, polymer, and antireflection film-forming composition JSR CORPORATION (JP) 2006-05-02 US disclosed
US-20040034155-A1 Acenaphthylene derivative, polymer, and antireflection film-forming composition JSR CORPORATION (JP) 2004-02-19 US disclosed
EP-1386904-A1 Acenaphthylene derivative, polymer, and antireflection film-forming composition JSR Corporation (JP) 2004-02-04 EP disclosed