Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25210653 | 0.87 | GPR119 (0.46) | GPR119KDM4EMAPTTHRB | |
| SCHEMBL25224709 | 0.82 | MLYCD (0.41) | — | |
| SCHEMBL23306598 | 0.81 | KDM4E (0.53) | GPR119KDM4EMAPTTHRBHPGDS | |
| SCHEMBL3897024 | 0.80 | KDM4E (0.52) | GPR119KDM4EMAPTTHRBHPGDS | |
| SCHEMBL3486582 | 0.79 | GPR119 (0.61) | GPR119 | |
| SCHEMBL30872409 | 0.78 | KDM4E (0.50) | GPR119KDM4EMAPTTHRBHPGDS | |
| SCHEMBL25198487 | 0.78 | PDK4 (0.45) | GPR119JAK1 | |
| SCHEMBL23604115 | 0.78 | GPR119 (0.46) | GPR119HPGDSJAK2JAK1 | |
| SCHEMBL25195768 | 0.77 | GPR119 (0.57) | GPR119KDM4EMAPTTHRBDDB1 | |
| SCHEMBL983152 | 0.76 | GPR119 (0.48) | GPR119KDM4EMAPTTHRBHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093728-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2023-06-01 | — | — | WO | disclosed |