Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK4 | Q13043 | 1/20 | 0.54 |
| ▸ | STK3 | Q13188 | 1/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 12/20 | 0.52 |
| ▸ | JAK2 | O60674 | 3/20 | 0.45 |
| ▸ | JAK1 | P23458 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | GRK5 | P34947 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30348045 | 0.77 | LRRK2 (0.45) | LRRK2ROCK2ROCK1CDC42BPBMAPK1 | |
| SCHEMBL25518134 | 0.77 | LRRK2 (0.45) | LRRK2ROCK2ROCK1CDC42BPBMAPK1 | |
| SCHEMBL13695778 | 0.76 | LRRK2 (0.55) | LRRK2ROCK2ROCK1CDC42BPB | |
| SCHEMBL25518654 | 0.75 | LRRK2 (0.53) | LRRK2ROCK2ROCK1CDC42BPBMAPK1 | |
| SCHEMBL30347624 | 0.75 | LRRK2 (0.53) | LRRK2ROCK2ROCK1CDC42BPBMAPK1 | |
| SCHEMBL25203990 | 0.75 | LRRK2 (0.53) | LRRK2JAK2ROCK2ROCK1CDC42BPB | |
| SCHEMBL30349042 | 0.74 | LRRK2 (0.52) | STK4STK3LRRK2ROCK2ROCK1 | |
| SCHEMBL25201354 | 0.74 | EGFR (0.50) | LRRK2ROCK2ROCK1CDC42BPBJAK3 | |
| SCHEMBL30348906 | 0.74 | LRRK2 (0.49) | LRRK2ROCK2ROCK1CDC42BPBJAK3 | |
| SCHEMBL25200736 | 0.74 | LRRK2 (0.49) | LRRK2ROCK2ROCK1CDC42BPBJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2023-06-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | DYRK1A, DYRK1B, DYRK2 | STK4 689/4885STK3 471/4885LRRK2 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.