Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.78 |
| ▸ | GUSB | P08236 | 8/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1252216 | 0.88 | DGAT1 (1.00) | DGAT1GUSBSLC2A1 | |
| SCHEMBL30385298 | 0.88 | DGAT1 (1.00) | DGAT1GUSBSLC2A1 | |
| SCHEMBL1252747 | 0.87 | DGAT1 (0.85) | DGAT1GUSBSLC2A1MAPTALDH1A1 | |
| SCHEMBL1252194 | 0.86 | DGAT1 (0.75) | DGAT1GUSBSLC2A1MAPTNPC1 | |
| SCHEMBL1252155 | 0.86 | DGAT1 (0.78) | DGAT1GUSBSLC2A1NPC1KMT2A | |
| SCHEMBL21354092 | 0.83 | DGAT1 (1.00) | DGAT1GUSBSLC2A1NPC1KMT2A | |
| SCHEMBL30565806 | 0.83 | DGAT1 (1.00) | DGAT1GUSBSLC2A1NPC1KMT2A | |
| SCHEMBL1252030 | 0.79 | DGAT1 (0.83) | DGAT1 | |
| SCHEMBL1252922 | 0.79 | DGAT1 (0.72) | DGAT1 | |
| SCHEMBL31326547 | 0.79 | DGAT1 (0.83) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023084449-A1 | DIAMINOCYCLOPENTYLPYRIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE OR DISORDER | NOVARTIS AG (CH) | 2023-05-19 | — | — | WO | disclosed |