Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25269073 | 1.00 | ACE (0.47) | ACEPPARAPPARGITGB3ITGA2B | |
| SCHEMBL25219574 | 1.00 | ACE (0.47) | ACEPPARAPPARGITGB3ITGA2B | |
| SCHEMBL30461868 | 0.89 | KLK5 (0.43) | CTSSCTSKSCN9ACYP3A4 | |
| SCHEMBL30461885 | 0.89 | KLK5 (0.43) | CTSSCTSKSCN9ACYP3A4 | |
| SCHEMBL25216220 | 0.85 | ITGA4 (0.52) | ACEPPARAPPARGITGB3ITGA2B | |
| SCHEMBL25268681 | 0.85 | ITGA4 (0.52) | ACEPPARAPPARGITGB3ITGA2B | |
| SCHEMBL29908039 | 0.83 | ACE (0.57) | ACEPPARAPPARGITGB3ITGA2B | |
| SCHEMBL1350266 | 0.83 | ACE (0.57) | ACEPPARAPPARGITGB3ITGA2B | |
| SCHEMBL1350265 | 0.83 | ACE (0.57) | ACEPPARAPPARGITGB3ITGA2B | |
| SCHEMBL3485116 | 0.83 | ACE (0.57) | ACEPPARAPPARGITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107597-A2 | BICYCLIC HETEROAROMATIC AMIDE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |