SCHEMBL1350265

SCHEMBL1350265

CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1Cl)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ACE P12821 2/20 0.57
CTSS P25774 6/20 0.55
CTSK P43235 5/20 0.55
PPARA Q07869 6/20 0.52
PPARG P37231 5/20 0.52
PTPN1 P18031 1/20 0.52
SCN9A Q15858 2/20 0.51
PPARD Q03181 2/20 0.50
SCN10A Q9Y5Y9 1/20 0.50
CTSL P07711 1/20 0.50
CTSB P07858 1/20 0.50
IDO1 P14902 1/20 0.48
ITGB3 P05106 1/20 0.48
ITGA2B P08514 1/20 0.48
MC4R P32245 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29908039 1.00 ACE (0.57) ACECTSSCTSKPPARAPPARG
SCHEMBL1350266 1.00 ACE (0.57) ACECTSSCTSKPPARAPPARG
SCHEMBL3485116 1.00 ACE (0.57) ACECTSSCTSKPPARAPPARG
SCHEMBL30962391 0.90 CTSS (0.53) ACECTSSCTSKPPARAPPARG
SCHEMBL25270309 0.88 KLK5 (0.52) ACECTSSCTSKSCN9ASCN10A
SCHEMBL25217471 0.88 KLK5 (0.52) ACECTSSCTSKSCN9ASCN10A
SCHEMBL22287759 0.88 CTSS (0.53) ACECTSSCTSKPPARAPPARG
SCHEMBL22287760 0.88 CTSS (0.53) ACECTSSCTSKPPARAPPARG
SCHEMBL1336069 0.87 CTSK (0.55) ACECTSSCTSKPPARAPPARG
SCHEMBL6123222 0.87 SCN9A (0.59) ACECTSSCTSKPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104910046-B Phenylacetylene derivative with double chiral carbon atoms on pendant group and preparation method and application thereof 哈尔滨工程大学 2017-05-24 CN claimed
CN-104910039-A Functional phenylacetylene compound and preparation method thereof UNIV HARBIN ENG 2015-09-16 CN claimed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
EP-4534524-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PeptiDream Inc. (JP) 2025-04-09 EP disclosed
US-20240057599-A1 METHODS FOR IMPROVING FRUIT QUALITY THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2024-02-22 US disclosed
CN-117529476-A Preparation of substituted 1, 2-diamino heterocyclic derivatives and their use as medicaments 亚飞络思制药公司 2024-02-06 CN disclosed
US-11812746-B2 Method of controlling fungal infections in plants THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2023-11-14 US disclosed
CN-116323596-A Interleukin-17 inhibitors 诺华股份有限公司 2023-06-23 CN disclosed
WO-2023107597-A2 BICYCLIC HETEROAROMATIC AMIDE COMPOUNDS AND USES THEREOF Kineta, Inc. (US) 2023-06-15 WO disclosed
US-11377425-B1 Small molecule modulators of IL-17 LEO PHARMA A/S (DK) 2022-07-05 US disclosed
US-11377425-B1 Small molecule modulators of IL-17 LEO PHARMA A/S (DK) 2022-07-05 US disclosed
EP-0719251-B1 BICYCLO (2.2.2) OCTANE DERIVATIVES CHOLECYSTOKININ AND/OR GASTRIN ANTAGONISTS BLACK JAMES FOUNDATION (GB) 1998-12-09 EP disclosed
EP-0866705-A1 FIBRINOGEN RECEPTOR ANTAGONISTS Merck & Co., Inc. (US) 1998-09-30 EP disclosed
US-5795907-A Gastin and CCK receptor ligands JAMES BLACK FOUNDATION LIMITED (GB) 1998-08-18 US disclosed
WO-1997014417-A1 FIBRINOGEN RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1997-04-24 WO disclosed
EP-0720601-A1 GASTRIN AND CCK RECEPTOR LIGANDS JAMES BLACK FOUNDATION LIMITED (GB) 1996-07-10 EP disclosed
EP-0719251-A1 BICYCLO (2.2.2) OCTANE DERIVATIVES CHOLECYSTOKININ AND/OR GASTRIN ANTAGONISTS JAMES BLACK FOUNDATION LIMITED (GB) 1996-07-03 EP disclosed
US-5514683-A LIGANDS FKOR CHOLECYSTOKININ OR GASTRIN RECEPTORS JAMES BLACK FOUNDATION LIMITED (GB) 1996-05-07 US disclosed
WO-1995005359-A1 BICYCLO (2.2.2) OCTANE DERIVATIVES CHOLECYSTOKININ AND/OR GASTRIN ANTAGONISTS JAMES BLACK FOUNDATION LIMITED (GB) 1995-02-23 WO disclosed
WO-1995004720-A2 GASTRIN AND CCK RECEPTOR LIGANDS BLACK JAMES FOUNDATION (GB) 1995-02-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11377425-B1 Small molecule modulators of IL-17 IL17A, IL15, IL2 ACE 2028/4885CTSS 757/4885CTSK 441/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 ACE 1944/4885CTSS 4022/4885CTSK 4661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.