SCHEMBL25217803

SCHEMBL25217803

O=C(O)c1ccc(CN2C(=O)S/C(=C\c3ccc(/C=C/C(=O)c4ccc(F)cc4)cc3)C2=O)cc1

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 9/20 0.71
▸ PTPN1 P18031 10/20 0.69
▸ ACP1 P24666 8/20 0.69
▸ PTPN2 P17706 4/20 0.63
▸ PTPRF P10586 2/20 0.63
▸ PTPRB P23467 2/20 0.63
▸ NLRP3 Q96P20 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25216522 0.92 PTPN1 (0.71) ENPP2PTPN1ACP1PTPN2PTPRF
SCHEMBL25285016 0.91 PTPN1 (0.84) ENPP2PTPN1ACP1PTPN2PTPRF
SCHEMBL25195356 0.91 PTPN1 (0.70) ENPP2PTPN1ACP1PTPN2PTPRF
SCHEMBL25191741 0.90 PTPN1 (0.69) ENPP2PTPN1ACP1PTPN2PTPRF
SCHEMBL25199034 0.90 PTPN1 (0.69) ENPP2PTPN1ACP1PTPN2PTPRF
SCHEMBL25196342 0.87 PTPN1 (0.68) ENPP2PTPN1ACP1PTPN2PTPRF
SCHEMBL25223704 0.87 PTPN1 (0.64) ENPP2PTPN1ACP1PTPN2PTPRF
SCHEMBL25193814 0.83 PTPN1 (0.68) ENPP2PTPN1ACP1PTPN2PTPRF
SCHEMBL25194385 0.83 PTPN1 (0.65) ENPP2PTPN1ACP1PTPN2PTPRF
SCHEMBL25205548 0.83 PTPN1 (0.64) ENPP2PTPN1ACP1PTPN2PTPRF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ENPP2 3762/4885PTPN1 1308/4885ACP1 2716/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ENPP2 1317/4885PTPN1 1520/4885ACP1 1174/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ENPP2 1317/4885PTPN1 1520/4885ACP1 1174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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