SCHEMBL25216522

SCHEMBL25216522

O=C(O)c1ccc(CN2C(=O)S/C(=C\c3ccc(/C=C/C(=O)c4ccccc4)cc3)C2=O)cc1

nearest known ligand 0.71

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 14/20 0.71
▸ ACP1 P24666 11/20 0.71
▸ PTPN2 P17706 5/20 0.71
▸ PTPRF P10586 2/20 0.71
▸ PTPRB P23467 2/20 0.71
▸ DUSP22 Q9NRW4 1/20 0.62
▸ NLRP3 Q96P20 2/20 0.60
▸ ENPP2 Q13822 3/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25195356 0.93 PTPN1 (0.70) PTPN1ACP1PTPN2PTPRFPTPRB
SCHEMBL25285016 0.93 PTPN1 (0.84) PTPN1ACP1PTPN2PTPRFPTPRB
SCHEMBL25191741 0.92 PTPN1 (0.69) PTPN1ACP1PTPN2PTPRFPTPRB
SCHEMBL25217803 0.92 ENPP2 (0.71) PTPN1ACP1PTPN2PTPRFPTPRB
SCHEMBL25199034 0.92 PTPN1 (0.69) PTPN1ACP1PTPN2PTPRFPTPRB
SCHEMBL25196342 0.89 PTPN1 (0.68) PTPN1ACP1PTPN2PTPRFPTPRB
SCHEMBL25194385 0.89 PTPN1 (0.65) PTPN1ACP1PTPN2PTPRFPTPRB
SCHEMBL25193814 0.89 PTPN1 (0.68) PTPN1ACP1PTPN2PTPRFPTPRB
SCHEMBL25223704 0.88 PTPN1 (0.64) PTPN1ACP1PTPN2PTPRFPTPRB
SCHEMBL25205548 0.88 PTPN1 (0.64) PTPN1ACP1PTPN2PTPRFPTPRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B PTPN1 1308/4885ACP1 2716/4885PTPN2 1928/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 PTPN1 1520/4885ACP1 1174/4885PTPN2 1912/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 PTPN1 1520/4885ACP1 1174/4885PTPN2 1912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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