Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 12/20 | 0.50 |
| ▸ | CTSK | P43235 | 11/20 | 0.50 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3815064 | 0.82 | CTSS (0.58) | CTSSCTSKCTSLCTSBPTPN1 | |
| SCHEMBL29907919 | 0.81 | CTSS (0.60) | CTSSCTSKCTSLCTSBPTPN1 | |
| SCHEMBL3812341 | 0.81 | CTSS (0.60) | CTSSCTSKCTSLCTSBPTPN1 | |
| SCHEMBL17912348 | 0.81 | CTSS (0.60) | CTSSCTSKCTSLCTSBPTPN1 | |
| SCHEMBL29842925 | 0.81 | CTSS (0.60) | CTSSCTSKCTSLCTSBPTPN1 | |
| SCHEMBL3812344 | 0.81 | CTSS (0.60) | CTSSCTSKCTSLCTSBPTPN1 | |
| SCHEMBL25219069 | 0.75 | DPP4 (0.56) | — | |
| SCHEMBL4847806 | 0.74 | PTPN1 (0.45) | CTSSCTSKCTSLCTSBKMT2A | |
| SCHEMBL30461860 | 0.73 | MC4R (0.52) | CTSSCTSKCTSLCTSBKMT2A | |
| SCHEMBL5969521 | 0.72 | PTPN1 (0.51) | CTSSCTSKCTSLCTSBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107597-A2 | BICYCLIC HETEROAROMATIC AMIDE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |