Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 14/20 | 0.60 |
| ▸ | CTSK | P43235 | 12/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.60 |
| ▸ | CTSL | P07711 | 3/20 | 0.56 |
| ▸ | CTSB | P07858 | 3/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812344 | 1.00 | CTSS (0.60) | CTSSCTSKPTPN1CTSLCTSB | |
| SCHEMBL3812341 | 1.00 | CTSS (0.60) | CTSSCTSKPTPN1CTSLCTSB | |
| SCHEMBL29842925 | 1.00 | CTSS (0.60) | CTSSCTSKPTPN1CTSLCTSB | |
| SCHEMBL17912348 | 1.00 | CTSS (0.60) | CTSSCTSKPTPN1CTSLCTSB | |
| SCHEMBL3815064 | 0.89 | CTSS (0.58) | CTSSCTSKPTPN1CTSLCTSB | |
| SCHEMBL5969521 | 0.87 | PTPN1 (0.51) | CTSSCTSKPTPN1CTSLCTSB | |
| SCHEMBL6463195 | 0.86 | PPARA (0.62) | CTSSCTSKPTPN1CTSLCTSB | |
| SCHEMBL6463193 | 0.86 | PPARA (0.62) | CTSSCTSKPTPN1CTSLCTSB | |
| SCHEMBL5001310 | 0.86 | PPARA (0.62) | CTSSCTSKPTPN1CTSLCTSB | |
| SCHEMBL5001306 | 0.86 | PPARA (0.62) | CTSSCTSKPTPN1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | NEW YORK UNIVERSITY (US) | 2026-01-01 | — | — | US | disclosed |
| US-12371461-B2 | Nemo coiled coil mimics and methods of using same | NEW YORK UNIVERSITY (US) | 2025-07-29 | — | — | US | disclosed |
| EP-3303367-B1 | STABILIZED MINIMAL COILED-COIL MIMETICS | UNIV NEW YORK (US) | 2025-06-18 | — | — | EP | disclosed |
| US-20240190930-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | UNIV NEW YORK (US) | 2024-06-13 | — | — | US | disclosed |
| US-20240049709-A1 | METHOD OF CONTROLLING FUNGAL INFECTIONS IN PLANTS | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION, (A.R.O), THE VOLCANI INSTITUTE (IL) | 2024-02-15 | — | — | US | disclosed |
| US-11891422-B2 | NEMO coiled coil mimics and methods of using same | NEW YORK UNIVERSITY (US) | 2024-02-06 | — | — | US | disclosed |
| US-20220289802-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | CORNELL UNIVERSITY | 2022-09-15 | — | — | US | disclosed |
| US-11440938-B2 | Stabilized minimal coiled-coil mimetics | NEW YORK UNIVERSITY (US) | 2022-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371461-B2 | Nemo coiled coil mimics and methods of using same | COIL, CALCOCO2, NCAPH | CTSS 4120/4885CTSK 4487/4885PTPN1 3919/4885 |
| US-11440938-B2 | Stabilized minimal coiled-coil mimetics | COIL, CALCOCO2, SMC2 | CTSS 3193/4885CTSK 4421/4885PTPN1 2039/4885 |
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | DDX21, PHAX, RBX1 | CTSS 4503/4885CTSK 4676/4885PTPN1 2490/4885 |
| US-11891422-B2 | NEMO coiled coil mimics and methods of using same | COIL, CALCOCO2, NCAPH | CTSS 4120/4885CTSK 4487/4885PTPN1 3919/4885 |
| US-20220289802-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | COIL, CALCOCO2, NCAPH | CTSS 4120/4885CTSK 4487/4885PTPN1 3919/4885 |
| US-20240190930-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | COIL, CALCOCO2, NCAPH | CTSS 4194/4885CTSK 4515/4885PTPN1 3824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.