Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16561852 | 0.78 | GRM8 (0.42) | SLC7A5HSD17B10CYP3A4PKMALPI | |
| SCHEMBL17925377 | 0.78 | GRIA1 (0.40) | SLC7A5HSD17B10CYP3A4PKMALPI | |
| SCHEMBL15469208 | 0.71 | SLC7A5 (0.35) | SLC7A5HSD17B10CYP3A4PKMALPI | |
| SCHEMBL31754299 | 0.70 | SLC7A5 (0.45) | SLC7A5HSD17B10CYP3A4PKMALPI | |
| SCHEMBL25211649 | 0.70 | HDAC6 (0.45) | ALOX15 | |
| SCHEMBL25222631 | 0.70 | USP2 (0.41) | SLC7A5HSD17B10CYP3A4PKMALPI | |
| SCHEMBL4249863 | 0.69 | SLC7A5 (0.47) | SLC7A5HSD17B10CYP3A4PKMALPI | |
| SCHEMBL11559690 | 0.69 | SLC7A5 (0.47) | SLC7A5HSD17B10CYP3A4PKMALPI | |
| SCHEMBL22775417 | 0.69 | SLC7A5 (0.43) | SLC7A5HSD17B10CYP3A4PKMALPI | |
| SCHEMBL5514921 | 0.69 | FDPS (0.53) | SLC7A5HSD17B10CYP3A4PKMALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107597-A2 | BICYCLIC HETEROAROMATIC AMIDE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |