Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30542263 | 1.00 | SNCA (0.47) | SNCADGAT1PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL20392825 | 0.87 | SNCA (0.50) | SNCADGAT1PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL2220666 | 0.82 | SNCA (0.40) | SNCADGAT1ALDH1A1F2GLA | |
| SCHEMBL23247161 | 0.82 | SNCA (0.53) | SNCADGAT1PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL13274885 | 0.81 | SNCA (0.41) | SNCADGAT1ALDH1A1F2GLA | |
| SCHEMBL2267580 | 0.80 | DGAT1 (0.56) | SNCADGAT1APPMAOBNPC1 | |
| SCHEMBL13275325 | 0.80 | LPL (0.41) | SNCADGAT1LPLLIPG | |
| SCHEMBL189898 | 0.80 | DGAT1 (0.49) | SNCADGAT1APPMAOBNPC1 | |
| SCHEMBL25622918 | 0.79 | SNCA (0.43) | SNCADGAT1PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL25179630 | 0.77 | DGAT1 (0.46) | SNCADGAT1APPMAOBCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023103898-A1 | COMPOUND HAVING CLK AND DYRK INHIBITORY ACTIVITIES, PREPARATION METHOD THEREFOR AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2023-06-15 | — | — | WO | disclosed |
| WO-2023103898-A1 | COMPOUND HAVING CLK AND DYRK INHIBITORY ACTIVITIES, PREPARATION METHOD THEREFOR AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2023-06-15 | — | — | WO | disclosed |