Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | HPGD | P15428 | 4/20 | 0.66 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | APP | P05067 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30938830 | 0.86 | MAPT (0.57) | NPC1RAB9AMAPK1CYP3A4ALDH1A1 | |
| Vinyl Chloride SCHEMBL28172143 | 0.83 | NPC1 (0.80) | NPC1RAB9AMAPK1CYP3A4ALDH1A1 | |
| SCHEMBL14306014 | 0.82 | ABCG2 (0.67) | NPC1RAB9AMAPK1ABCG2MAPT | |
| SCHEMBL10990485 | 0.81 | ABCG2 (0.69) | NPC1RAB9AMAPK1CYP3A4ALDH1A1 | |
| SCHEMBL38652 | 0.81 | NPC1 (1.00) | NPC1RAB9AMAPK1CYP3A4ALDH1A1 | |
| SCHEMBL30382876 | 0.81 | CES2 (0.59) | MAPK1CYP3A4ALDH1A1HPGDABCG2 | |
| SCHEMBL11139626 | 0.81 | CES2 (0.59) | MAPK1CYP3A4ALDH1A1HPGDABCG2 | |
| SCHEMBL1514997 | 0.81 | NPC1 (1.00) | NPC1RAB9AMAPK1CYP3A4ALDH1A1 | |
| SCHEMBL29365072 | 0.81 | NPC1 (1.00) | NPC1RAB9AMAPK1CYP3A4ALDH1A1 | |
| SCHEMBL9328578 | 0.81 | HPGD (0.58) | NPC1RAB9AMAPK1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| CN-118388430-A | Pterocarpus astragalus chalcone compound, preparation method and medical application thereof | 安徽中医药大学 | 2024-07-26 | — | — | CN | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |