Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | CPS1 | P31327 | 12/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15226106 | 0.82 | CPS1 (0.61) | HPGDMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL9325799 | 0.82 | KDM4E (0.49) | HPGDMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL3311002 | 0.81 | MEN1 (0.53) | HPGDMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL3310996 | 0.81 | MEN1 (0.53) | HPGDMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL3310998 | 0.81 | MEN1 (0.53) | HPGDMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL25223207 | 0.81 | NPC1 (0.68) | HPGDMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL14306014 | 0.81 | ABCG2 (0.67) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL29639738 | 0.80 | ALDH1A1 (0.65) | HPGDMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL1051747 | 0.80 | CPS1 (0.63) | HPGDMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL531399 | 0.80 | ALDH1A1 (0.65) | HPGDMEN1LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602811-B | FXR receptor agonists | 轩竹生物科技有限公司 | 2021-11-16 | — | — | CN | disclosed |
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |
| EP-0361157-B1 | Phenyl pyridines | HOFFMANN LA ROCHE (CH) | 1994-03-02 | — | — | EP | disclosed |
| US-5284956-A | Liquid crystalline mixtures containing 2-(2-fluorophenyl) pyridines | HOFFMANN-LA ROCHE INC. (US) | 1994-02-08 | — | — | US | disclosed |
| EP-0361157-A1 | Phenyl pyridines | F. HOFFMANN-LA ROCHE AG (CH) | 1990-04-04 | — | — | EP | disclosed |