SCHEMBL25223578

SCHEMBL25223578

COc1ccc(C=CC(=O)c2c(O)cc(C)cc2OC2OC(CO)C(F)C(O)C2O)cc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ SLC5A1 P13866 9/20 0.50
▸ SLC5A2 P31639 8/20 0.50
▸ DPP4 P27487 2/20 0.50
▸ AKR1B1 P15121 1/20 0.50
▸ ABCG2 Q9UNQ0 1/20 0.49
▸ CA9 Q16790 3/20 0.48
▸ CA2 P00918 1/20 0.48
▸ SNCA P37840 1/20 0.47
▸ APP P05067 1/20 0.46
▸ TDP1 Q9NUW8 2/20 0.45
▸ GAA P10253 1/20 0.45
▸ NFKB1 P19838 1/20 0.45
▸ NFKB2 Q00653 1/20 0.45
▸ RELA Q04206 1/20 0.45
▸ CA12 O43570 2/20 0.43
▸ CA1 P00915 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30383241 1.00 SLC5A1 (0.50) SLC5A1SLC5A2DPP4AKR1B1ABCG2
SCHEMBL12807948 1.00 SLC5A1 (0.50) SLC5A1SLC5A2DPP4AKR1B1ABCG2
SCHEMBL30382841 1.00 SLC5A1 (0.50) SLC5A1SLC5A2DPP4AKR1B1ABCG2
Ethane SCHEMBL25223359 0.99 SLC5A1 (0.49) SLC5A1SLC5A2DPP4AKR1B1ABCG2
SCHEMBL25196619 0.90 SLC5A1 (0.51) SLC5A1SLC5A2DPP4AKR1B1ABCG2
SCHEMBL30382848 0.90 SLC5A1 (0.51) SLC5A1SLC5A2DPP4AKR1B1ABCG2
SCHEMBL25196890 0.90 SLC5A1 (0.50) SLC5A1SLC5A2DPP4AKR1B1SNCA
SCHEMBL30382747 0.90 SLC5A1 (0.50) SLC5A1SLC5A2DPP4AKR1B1SNCA
SCHEMBL12807953 0.82 SLC5A1 (0.72) SLC5A1SLC5A2
Neosakuranin SCHEMBL25191361 0.81 DPP4 (0.64) SLC5A1SLC5A2DPP4AKR1B1ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B SLC5A1 3752/4885SLC5A2 4208/4885DPP4 4226/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 SLC5A1 4485/4885SLC5A2 4756/4885DPP4 3670/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 SLC5A1 4485/4885SLC5A2 4756/4885DPP4 3670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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