SCHEMBL30382747

SCHEMBL30382747

Cc1cc(O)c(C(=O)C=Cc2ccccc2)c(OC2OC(CO)C(F)C(O)C2O)c1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ SLC5A1 P13866 7/20 0.50
▸ SLC5A2 P31639 7/20 0.50
▸ AKR1B1 P15121 1/20 0.46
▸ DPP4 P27487 1/20 0.46
▸ GAA P10253 1/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45
▸ SLC28A3 Q9HAS3 4/20 0.45
▸ MAPT P10636 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ KCNA3 P22001 1/20 0.44
▸ NPSR1 Q6W5P4 1/20 0.44
▸ TP53 P04637 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ ATM Q13315 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ SNCA P37840 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25196890 1.00 SLC5A1 (0.50) SLC5A1SLC5A2AKR1B1DPP4GAA
SCHEMBL30383241 0.90 SLC5A1 (0.50) SLC5A1SLC5A2AKR1B1DPP4GAA
SCHEMBL12807948 0.90 SLC5A1 (0.50) SLC5A1SLC5A2AKR1B1DPP4GAA
SCHEMBL25223578 0.90 SLC5A1 (0.50) SLC5A1SLC5A2AKR1B1DPP4GAA
SCHEMBL30382841 0.90 SLC5A1 (0.50) SLC5A1SLC5A2AKR1B1DPP4GAA
Ethane SCHEMBL25223359 0.90 SLC5A1 (0.49) SLC5A1SLC5A2AKR1B1DPP4GAA
SCHEMBL25201218 0.82 SLC28A3 (0.64) SLC5A1SLC5A2AKR1B1DPP4GAA
SCHEMBL30384588 0.82 SLC28A3 (0.64) SLC5A1SLC5A2AKR1B1DPP4GAA
SCHEMBL25208547 0.82 SLC28A3 (0.64) SLC5A1SLC5A2AKR1B1DPP4GAA
SCHEMBL13553044 0.81 SLC28A3 (0.66) SLC5A1SLC5A2SLC28A3MAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
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