Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | AKT1 | P31749 | 6/20 | 0.42 |
| ▸ | AKT2 | P31751 | 2/20 | 0.40 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25229793 | 0.93 | AKT1 (0.42) | MEN1KMT2AAKT1AKT2AKT3 | |
| SCHEMBL25281209 | 0.92 | MEN1 (0.44) | MEN1KMT2AAKT1AKT2AKT3 | |
| SCHEMBL25280892 | 0.87 | KIT (0.44) | MEN1AKT1 | |
| SCHEMBL30405237 | 0.87 | KIT (0.44) | MEN1AKT1 | |
| SCHEMBL30456670 | 0.86 | MEN1 (0.44) | MEN1KMT2AAKT1 | |
| SCHEMBL25277100 | 0.86 | MEN1 (0.44) | MEN1KMT2AAKT1 | |
| SCHEMBL25716737 | 0.85 | HTT (0.46) | MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL25274939 | 0.85 | AKT1 (0.42) | MEN1KMT2AAKT1AKT2AKT3 | |
| SCHEMBL25229702 | 0.85 | AKT1 (0.44) | AKT1AKT2AKT3JAK3 | |
| SCHEMBL25633236 | 0.84 | HTT (0.52) | MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107687-A1 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |