Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 9/20 | 0.44 |
| ▸ | AKT2 | P31751 | 5/20 | 0.42 |
| ▸ | AKT3 | Q9Y243 | 5/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | AKT1S1 | Q96B36 | 1/20 | 0.40 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.39 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25234444 | 0.92 | PDGFRB (0.41) | AKT1PDGFRBJAK3 | |
| SCHEMBL30406267 | 0.92 | PDGFRB (0.41) | AKT1PDGFRBJAK3 | |
| SCHEMBL25275689 | 0.91 | PDGFRB (0.43) | AKT1AKT2AKT3KITPDGFRB | |
| SCHEMBL25225988 | 0.87 | KIT (0.49) | KITPDGFRB | |
| SCHEMBL30455937 | 0.87 | KIT (0.49) | KITPDGFRB | |
| SCHEMBL25725161 | 0.86 | AURKA (0.47) | KITAURKA | |
| SCHEMBL25224450 | 0.85 | MEN1 (0.44) | AKT1AKT2AKT3JAK3 | |
| SCHEMBL25633293 | 0.84 | HTT (0.52) | KITAURKA | |
| SCHEMBL25279193 | 0.84 | AKT1 (0.40) | AKT1PDGFRBPDGFRA | |
| SCHEMBL25630561 | 0.84 | KIT (0.41) | AKT1KITAURKAIP6K1IP6K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107687-A1 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |