Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 10/20 | 0.52 |
| ▸ | KYNU | Q16719 | 1/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25271394 | 1.00 | TRPM8 (0.55) | TRPM8CASP1KYNUCTRB1ATM | |
| SCHEMBL25222634 | 1.00 | TRPM8 (0.55) | TRPM8CASP1KYNUCTRB1ATM | |
| SCHEMBL3331611 | 0.87 | TRPM8 (0.67) | TRPM8KYNUCTRB1ATMALDH1A1 | |
| SCHEMBL3333997 | 0.87 | TRPM8 (0.51) | TRPM8CASP1KYNUCTRB1ATM | |
| SCHEMBL3327107 | 0.86 | ATM (0.51) | TRPM8CASP1KYNUCTRB1ATM | |
| SCHEMBL3327113 | 0.86 | ATM (0.51) | TRPM8CASP1KYNUCTRB1ATM | |
| SCHEMBL9749127 | 0.86 | ATM (0.56) | TRPM8CASP1CTRB1ATMCTSK | |
| SCHEMBL19859590 | 0.86 | ATM (0.56) | TRPM8CASP1CTRB1ATMCTSK | |
| SCHEMBL3202235 | 0.86 | ATM (0.56) | TRPM8CASP1CTRB1ATMCTSK | |
| SCHEMBL3328135 | 0.85 | TRPM8 (0.54) | TRPM8CASP1KYNUCTRB1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023108031-A1 | PRODRUGS FOR COMPOUNDS SPECIFIC TO GRANZYME B AND USES THEREOF | CYTOSITE BIOPHARMA INC. (US) | 2023-06-15 | — | — | WO | disclosed |