Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | ELANE | P08246 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 6/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.52 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19859590 | 1.00 | ATM (0.56) | ATMELANECASP1TRPM8CASP3 | |
| SCHEMBL3202235 | 1.00 | ATM (0.56) | ATMELANECASP1TRPM8CASP3 | |
| SCHEMBL15395673 | 0.90 | ATM (0.54) | ATMELANETRPM8CTSKCTRB1 | |
| SCHEMBL31264459 | 0.90 | CTSL (0.56) | ATMELANECASP1TRPM8CASP3 | |
| SCHEMBL13202029 | 0.90 | CTSL (0.56) | ATMELANECASP1TRPM8CASP3 | |
| SCHEMBL9937089 | 0.89 | TRPM8 (0.55) | ATMELANECASP1TRPM8CTSK | |
| SCHEMBL9937088 | 0.89 | TRPM8 (0.55) | ATMELANECASP1TRPM8CTSK | |
| SCHEMBL9831451 | 0.89 | CTSK (0.46) | ATMELANECASP1TRPM8CASP3 | |
| SCHEMBL6044628 | 0.89 | PSMB1 (0.58) | ATMELANETRPM8CTSKCTRB1 | |
| SCHEMBL6044396 | 0.89 | PSMB1 (0.58) | ATMELANETRPM8CTSKCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219852-B1 | CHARTREUSIN DERIVATIVES, SALTS THEREOF, ANTITUMOROUS COMPOSITIONS CONTAINING THE SAME, AND PROCESSES FOR PRODUCING THE SAME | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-02-05 | — | — | EP | disclosed |
| US-5064945-A | Antitumor Agents | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1991-11-12 | — | — | US | disclosed |
| US-4927919-A | ANTITUMOR AGENTS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1990-05-22 | — | — | US | disclosed |
| EP-0159708-B1 | CHARTREUSIN DERIVATIVES, SALTS THEREOF, ANTITUMOROUS COMPOSITIONS CONTAINING THE SAME, AND PROCESSES FOR PRODUING THE SAME | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1989-12-13 | — | — | EP | disclosed |
| US-4760136-A | Chartreusin derivatives and salts thereof | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0219852-A2 | Chartreusin derivatives, salts thereof, antitumorous compositions containing the same, and processes for producing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-04-29 | — | — | EP | disclosed |
| EP-0159708-A2 | Chartreusin derivatives, salts thereof, antitumorous compositions containing the same, and processes for produing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1985-10-30 | — | — | EP | disclosed |