SCHEMBL25228686

SCHEMBL25228686

C=C[Si](CCCCCCCC)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.39
LMNA P02545 1/20 0.37
THRB P10828 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
FAAH O00519 1/20 0.32
EPHX1 P07099 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25206450 1.00 TSHR (0.39) TSHRLMNATHRBZDHHC20ZDHHC2
SCHEMBL25211123 1.00 TSHR (0.39) TSHRLMNATHRBZDHHC20ZDHHC2
SCHEMBL4199404 1.00 TSHR (0.39) TSHRLMNATHRBZDHHC20ZDHHC2
SCHEMBL6909484 1.00 TSHR (0.39) TSHRLMNATHRBZDHHC20ZDHHC2
SCHEMBL25233467 1.00 TSHR (0.39) TSHRLMNATHRBZDHHC20ZDHHC2
SCHEMBL25205617 1.00 TSHR (0.39) TSHRLMNATHRBZDHHC20ZDHHC2
SCHEMBL28314978 0.98 TSHR (0.36) TSHRLMNATHRBZDHHC20ZDHHC2
SCHEMBL1066665 0.91 TSHR (0.35) TSHRLMNAALDH1A1
SCHEMBL931740 0.89
SCHEMBL930736 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4212494-B1 POLYMER HAVING DISPERSING FUNCTION AND USE THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2026-05-06 EP disclosed
US-12091512-B2 Organopolysiloxane and coating composition containing organopolysiloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-09-17 US disclosed
EP-4074753-B1 ORGANOPOLYSILOXANE AND COATING COMPOSITION CONTAINING ORGANOPOLYSILOXANE SHINETSU CHEMICAL CO (JP) 2023-12-13 EP disclosed
US-20230391941-A1 POLYMER HAVING DISPERSING FUNCTION, POLYCARBOXYLIC ACID CEMENT DISPERSANT, PREPARATION METHOD THEREFOR AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2023-12-07 US disclosed
US-20230286862-A1 POLYMER HAVING DISPERSING FUNCTION, OIL WELL CEMENT DISPERSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2023-09-14 US disclosed
EP-4212494-A1 POLYMER HAVING DISPERSING FUNCTION, POLYCARBOXYLIC ACID CEMENT DISPERSANT, PREPARATION METHOD THEREFOR AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2023-07-19 EP disclosed
EP-4190829-A1 POLYMER HAVING DISPERSING FUNCTION, OIL WELL CEMENT DISPERSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2023-06-07 EP disclosed
US-20220340715-A1 ORGANOPOLYSILOXANE AND COATING COMPOSITION CONTAINING ORGANOPOLYSILOXANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-10-27 US disclosed
CN-115216020-A Organopolysiloxane and coating composition containing organopolysiloxane 信越化学工业株式会社 2022-10-21 CN disclosed
EP-4074753-A2 ORGANOPOLYSILOXANE AND COATING COMPOSITION CONTAINING ORGANOPOLYSILOXANE Shin-Etsu Chemical Co., Ltd. (JP) 2022-10-19 EP disclosed
WO-2022078046-A1 POLYMER HAVING DISPERSING FUNCTION, POLYCARBOXYLIC ACID CEMENT DISPERSANT, PREPARATION METHOD THEREFOR AND USE THEREOF 中国石油化工股份有限公司 2022-04-21 WO disclosed
WO-2022033588-A1 POLYMER HAVING DISPERSING FUNCTION, OIL WELL CEMENT DISPERSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国石油化工股份有限公司 2022-02-17 WO disclosed
CN-110183666-A A kind of vinylsiloxane grafting containing hydrogen silicone oil and preparation method thereof 安徽硅宝有机硅新材料有限公司 2019-08-30 CN disclosed
CN-104672274-B Contain a variety of functional group's polyhedral oligomeric silsesquioxanes and its synthetic method and application 杭州师范大学 2017-11-14 CN disclosed
CN-104672274-A Polyhedral oligomeric silsesquioxane containing multiple functional groups as well as synthetic method and application of polyhedral oligomeric silsesquioxane UNIV HANGZHOU NORMAL 2015-06-03 CN disclosed