SCHEMBL4199404

SCHEMBL4199404

C=C[Si](CCCCCCCCCCCCCCCCCC)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.39
LMNA P02545 1/20 0.37
THRB P10828 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
FAAH O00519 1/20 0.32
EPHX1 P07099 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25206450 1.00 TSHR (0.39) TSHRLMNATHRBZDHHC20ZDHHC2
SCHEMBL25211123 1.00 TSHR (0.39) TSHRLMNATHRBZDHHC20ZDHHC2
SCHEMBL6909484 1.00 TSHR (0.39) TSHRLMNATHRBZDHHC20ZDHHC2
SCHEMBL25233467 1.00 TSHR (0.39) TSHRLMNATHRBZDHHC20ZDHHC2
SCHEMBL25205617 1.00 TSHR (0.39) TSHRLMNATHRBZDHHC20ZDHHC2
SCHEMBL25228686 1.00 TSHR (0.39) TSHRLMNATHRBZDHHC20ZDHHC2
SCHEMBL28314978 0.98 TSHR (0.36) TSHRLMNATHRBZDHHC20ZDHHC2
SCHEMBL1066665 0.91 TSHR (0.35) TSHRLMNAALDH1A1
SCHEMBL931740 0.89
SCHEMBL930736 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112250385-A Light flame-retardant heat-insulating material for building exterior wall and preparation method thereof 舒城诚鑫建材有限公司 2021-01-22 CN claimed
CN-105174895-B A kind of preparation method of light-weight water-proof thermal insulation material used for building exterior wall 北京高能时代环境技术股份有限公司 2018-06-15 CN claimed
EP-0974596-B1 Method for preparation of alkoxysilanes having reduced halide content DOW CORNING (US) 2003-03-05 EP claimed
EP-0974596-A2 Method for preparation of alkoxysilanes having reduced halide content DOW CORNING CORPORATION (US) 2000-01-26 EP claimed
EP-4212494-B1 POLYMER HAVING DISPERSING FUNCTION AND USE THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2026-05-06 EP disclosed
US-20230391941-A1 POLYMER HAVING DISPERSING FUNCTION, POLYCARBOXYLIC ACID CEMENT DISPERSANT, PREPARATION METHOD THEREFOR AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2023-12-07 US disclosed
US-20230286862-A1 POLYMER HAVING DISPERSING FUNCTION, OIL WELL CEMENT DISPERSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2023-09-14 US disclosed
EP-4212494-A1 POLYMER HAVING DISPERSING FUNCTION, POLYCARBOXYLIC ACID CEMENT DISPERSANT, PREPARATION METHOD THEREFOR AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2023-07-19 EP disclosed
EP-4190829-A1 POLYMER HAVING DISPERSING FUNCTION, OIL WELL CEMENT DISPERSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2023-06-07 EP disclosed
CN-112250385-A Light flame-retardant heat-insulating material for building exterior wall and preparation method thereof 舒城诚鑫建材有限公司 2021-01-22 CN disclosed
CN-105174895-B A kind of preparation method of light-weight water-proof thermal insulation material used for building exterior wall 北京高能时代环境技术股份有限公司 2018-06-15 CN disclosed
EP-2032588-B1 METHOD FOR PREPARATION OF ALKOXYSILANES HAVING REDUCED HALIDE CONTENT DOW CORNING (US) 2012-08-08 EP disclosed
US-20090270646-A1 METHOD FOR PREPARATION OF ALKOXYSILANES HAVING REDUCED HALIDE DOW CORNING CORPORATION 2009-10-29 US disclosed
EP-2032588-A2 METHOD FOR PREPARATION OF ALKOXYSILANES HAVING REDUCED HALIDE CONTENT Dow Corning Corporation (US) 2009-03-11 EP disclosed
WO-2007149201-A2 METHOD FOR PREPARATION OF ALKOXYSILANES HAVING REDUCED HALIDE CONTENT DOW CORNING CORPORATION (US) 2007-12-27 WO disclosed
EP-0974596-B1 Method for preparation of alkoxysilanes having reduced halide content DOW CORNING (US) 2003-03-05 EP disclosed
EP-0974596-A2 Method for preparation of alkoxysilanes having reduced halide content DOW CORNING CORPORATION (US) 2000-01-26 EP disclosed
US-5914421-A Method for preparation of alkoxysilanes having reduced halide content DOW CORNING CORPORATION (US) 1999-06-22 US disclosed