Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4199404 | 0.98 | TSHR (0.39) | TSHRLMNAALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL6909484 | 0.98 | TSHR (0.39) | TSHRLMNAALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL25205617 | 0.98 | TSHR (0.39) | TSHRLMNAALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL25206450 | 0.98 | TSHR (0.39) | TSHRLMNAALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL25228686 | 0.98 | TSHR (0.39) | TSHRLMNAALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL25233467 | 0.98 | TSHR (0.39) | TSHRLMNAALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL25211123 | 0.98 | TSHR (0.39) | TSHRLMNAALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL1066665 | 0.93 | TSHR (0.35) | TSHRLMNAALDH1A1 | |
| SCHEMBL931740 | 0.91 | — | — | |
| SCHEMBL930736 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110183666-A | A kind of vinylsiloxane grafting containing hydrogen silicone oil and preparation method thereof | 安徽硅宝有机硅新材料有限公司 | 2019-08-30 | — | — | CN | disclosed |