SCHEMBL25229209

SCHEMBL25229209

CN(C)C(=O)C(=O)c1c[nH]c2cccc(O)c12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 7/20 0.50
▸ HTR2C P28335 6/20 0.50
▸ HTR2B P41595 6/20 0.50
▸ GAA P10253 2/20 0.49
▸ NPSR1 Q6W5P4 1/20 0.49
▸ HTR1A P08908 3/20 0.48
▸ DRD1 P21728 1/20 0.48
▸ HTR1D P28221 1/20 0.48
▸ HTR1B P28222 1/20 0.48
▸ HTR1E P28566 1/20 0.48
▸ ADORA2A P29274 1/20 0.48
▸ ADORA2B P29275 1/20 0.48
▸ HTR7 P34969 1/20 0.48
▸ DRD3 P35462 1/20 0.48
▸ HTR5A P47898 1/20 0.48
▸ HTR6 P50406 1/20 0.48
▸ ALDH1A1 P00352 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25423753 0.84 HTR2A (0.46) HTR2AHTR2CHTR2BGAANPSR1
SCHEMBL25678359 0.84 HTR2A (0.47) HTR2AHTR2CHTR2BALDH1A1POLB
SCHEMBL20898145 0.84 PBRM1 (0.47) HTR2AHTR2CHTR2BGAANPSR1
SCHEMBL24746654 0.81 HTR6 (0.49) HTR2AHTR2CHTR2BHTR1AHTR7
SCHEMBL31310148 0.80 SLC6A4 (0.44) HTR2AHTR2CHTR2BGAANPSR1
SCHEMBL25118462 0.79 SLC22A6 (0.47) HTR2AHTR2CHTR2BHTR1AHTR6
SCHEMBL20898147 0.79 GAA (0.51) HTR2AHTR2CHTR2BGAANPSR1
SCHEMBL2003960 0.77 GAA (0.58) HTR2AHTR2CHTR2BGAANPSR1
SCHEMBL29414387 0.76 PBRM1 (0.62) ALDH1A1MEN1POLBKMT2ANR4A2
SCHEMBL4215371 0.76 PBRM1 (0.62) ALDH1A1MEN1POLBKMT2ANR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590060-B2 Scalable synthetic route for psilocin and psilocybin MINDSET PHARMA INC. (CA) 2026-03-31 — — US disclosed
US-20230286916-A1 SCALABLE SYNTHETIC ROUTE FOR PSILOCIN AND PSILOCYBIN MINDSET PHARMA INC. (CA) 2023-09-14 — — US disclosed
US-20230286916-A1 SCALABLE SYNTHETIC ROUTE FOR PSILOCIN AND PSILOCYBIN MINDSET PHARMA INC. (CA) 2023-09-14 — — US disclosed
US-20230286916-A1 SCALABLE SYNTHETIC ROUTE FOR PSILOCIN AND PSILOCYBIN MINDSET PHARMA INC. (CA) 2023-09-14 — — US disclosed
CN-116348448-A Scalable synthetic routes to siloxine and silodosin 明德赛特制药公司 2023-06-27 — — CN disclosed
EP-4185565-A1 SCALABLE SYNTHETIC ROUTE FOR PSILOCIN AND PSILOCYBIN Mindset Pharma Inc. (CA) 2023-05-31 — — EP disclosed
WO-2022016289-A1 SCALABLE SYNTHETIC ROUTE FOR PSILOCIN AND PSILOCYBIN MINDSET PHARMA INC. (CA) 2022-01-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590060-B2 Scalable synthetic route for psilocin and psilocybin HTR2C, HTR1B, HTR2B HTR2A 8/4885HTR2C 1/4885HTR2B 3/4885
US-20230286916-A1 SCALABLE SYNTHETIC ROUTE FOR PSILOCIN AND PSILOCYBIN HTR1B, HTR2B, DRD2 HTR2A 15/4885HTR2C 5/4885HTR2B 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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