Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25204910 | 0.86 | MEN1 (0.59) | MEN1KMT2AALDH1A1HPGDSLC6A4 | |
| SCHEMBL26161885 | 0.84 | MEN1 (0.56) | MEN1KMT2AALDH1A1SLC6A4TAAR1 | |
| SCHEMBL25224327 | 0.83 | TAAR1 (0.62) | MEN1KMT2AALDH1A1HPGDSLC6A4 | |
| SCHEMBL25207759 | 0.83 | MEN1 (0.55) | MEN1KMT2AALDH1A1HPGDSLC6A4 | |
| SCHEMBL25206921 | 0.83 | MEN1 (0.52) | MEN1KMT2AALDH1A1HPGDSLC6A4 | |
| SCHEMBL31468730 | 0.82 | TAAR1 (0.65) | MEN1KMT2AALDH1A1HPGDSLC6A4 | |
| SCHEMBL5299284 | 0.82 | TAAR1 (0.65) | MEN1KMT2AALDH1A1HPGDSLC6A4 | |
| SCHEMBL25219439 | 0.82 | MEN1 (0.53) | MEN1KMT2AALDH1A1HPGDSLC6A4 | |
| SCHEMBL25224748 | 0.82 | MEN1 (0.54) | MEN1KMT2AALDH1A1SLC6A4TAAR1 | |
| SCHEMBL25236074 | 0.81 | MEN1 (0.59) | MEN1KMT2AALDH1A1HPGDSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4436964-A1 | ANALOGUES OF MDMA FOR MODULATING SERT, DAT, AND / OR NET ACTIVITY | The University Of Western Australia (AU) | 2024-10-02 | — | — | EP | disclosed |
| WO-2023092195-A1 | ANALOGUES OF MDMA FOR MODULATING SERT, DAT, AND / OR NET ACTIVITY | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2023-06-01 | — | — | WO | disclosed |
| WO-2023092195-A1 | ANALOGUES OF MDMA FOR MODULATING SERT, DAT, AND / OR NET ACTIVITY | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2023-06-01 | — | — | WO | disclosed |