SCHEMBL5299284

SCHEMBL5299284

CC(Cc1ccc2c(c1)OCO2)NCc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.65
SLC6A4 P31645 3/20 0.65
SLC6A2 P23975 2/20 0.65
SLC6A3 Q01959 2/20 0.65
CYP2D6 P10635 1/20 0.65
MEN1 O00255 1/20 0.64
KMT2A Q03164 1/20 0.64
ALDH1A1 P00352 2/20 0.63
KDM4E B2RXH2 1/20 0.63
TSHR P16473 1/20 0.63
SIGMAR1 Q99720 1/20 0.59
HPGD P15428 2/20 0.56
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31468730 1.00 TAAR1 (0.65) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL10715342 0.86 ALDH1A1 (0.64) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Hydrochloric Acid SCHEMBL10714213 0.85 MEN1 (0.63) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL25858236 0.85 TAAR1 (0.60) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL25188324 0.82 TAAR1 (0.72) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL896903 0.82 TAAR1 (0.72) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL715096 0.82 TAAR1 (0.72) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL29350327 0.82 TAAR1 (0.72) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL30434262 0.82 TAAR1 (0.72) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL30503037 0.82 TAAR1 (0.72) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US claimed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 EP claimed
US-20250136548-A1 FUNCTIONALIZED ALKYLAMINES TERRAN BIOSCIENCES INC (US) 2025-05-01 US claimed
WO-2024107445-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES, INC. (US) 2024-05-23 WO claimed
WO-2023141595-A2 FUNCTIONALIZED ALKYLAMINES TERRAN BIOSCIENCES, INC. (US) 2023-07-27 WO claimed
WO-2022221942-A1 PREVENTION OF DRUG DIVERSION BETTERLIFE PHARMA INC. (CA) 2022-10-27 WO claimed
US-20260138985-A1 Azepino-Indoles for the Treatment of Neurological and Psychiatric Disorders TERRAN BIOSCIENCES INC (US) 2026-05-21 US disclosed
US-20260138948-A1 N-SUBSTITUTED INDOLES AS 5-HYDROXYTRYPTAMINE (5-HT) SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS TERRAN BIOSCIENCES INC (US) 2026-05-21 US disclosed
US-20260125345-A1 SALTS AND SOLID FORMS OF N-ETHYL-2-(5-FLUORO-1H-INDOL-3-YL)-N-METHYLETHAN-1-AMINE TERRAN BIOSCIENCES INC. 2026-05-07 US disclosed
US-12612364-B2 Salts and solid forms of 4-hydroxy-N,N-diisopropyltryptamine hemi-glutarate and hemi-succinate TERRAN BIOSCIENCES INC. (US) 2026-04-28 US disclosed
US-20260108544-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS LLC (US) 2026-04-23 US disclosed
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2026-04-23 US disclosed
EP-4720030-A1 ASYMMETRIC PHENYLALKYLAMINES Alexander Shulgin Research Institute, Inc. (US) 2026-04-08 EP disclosed
US-20190142851-A1 COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID CAAMTECH, INC. 2019-05-16 US disclosed
US-20150025063-A1 Antiparkinsonian Action of Phenylisopropylamines UNIV DUKE (US) 2015-01-22 US disclosed
US-8877802-B2 Antiparkinsonian action of phenylisopropylamines Duke Univerity (US) 2014-11-04 US disclosed
WO-2007016190-A2 ANTIPARKINSONIAN ACTION OF PHENYLISOPROPYLAMINES DUKE UNIVERSITY (US) 2007-02-08 WO disclosed
US-20070027208-A1 Antiparkinsonian Action of Phenylisopropylamines NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-02-01 US disclosed
US-4376780-A Novel phenethylamine derivatives and bronchdilator containing the same EISAI CO., LTD. (JP) 1983-03-15 US disclosed
US-4317930-A Phenethylamine derivatives and bronchdilator containing the same EISAI CO., LTD. (JP) 1982-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190142851-A1 COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID CNR1, CNR2, HTR5A TAAR1 84/4885SLC6A4 317/4885SLC6A2 1008/4885
US-20260138948-A1 N-SUBSTITUTED INDOLES AS 5-HYDROXYTRYPTAMINE (5-HT) SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS HTR1D, HTR2C, TPH1 TAAR1 117/4885SLC6A4 15/4885SLC6A2 24/4885
US-20260138985-A1 Azepino-Indoles for the Treatment of Neurological and Psychiatric Disorders TPH2, TPH1, HTR1D TAAR1 290/4885SLC6A4 28/4885SLC6A2 30/4885
US-12612364-B2 Salts and solid forms of 4-hydroxy-N,N-diisopropyltryptamine hemi-glutarate and hemi-succinate SLC6A4, DLST, GRIN2D TAAR1 3871/4885SLC6A4 1/4885SLC6A2 5/4885
US-20070027208-A1 Antiparkinsonian Action of Phenylisopropylamines PNMT, SNCA, COMT TAAR1 1075/4885SLC6A4 178/4885SLC6A2 97/4885
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES PDE9A, PDE3A, PDE2A TAAR1 79/4885SLC6A4 45/4885SLC6A2 49/4885
US-20150025063-A1 Antiparkinsonian Action of Phenylisopropylamines PNMT, SNCA, COMT TAAR1 1075/4885SLC6A4 178/4885SLC6A2 97/4885
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND ADRA2C, ADRB3, ADRA2B TAAR1 51/4885SLC6A4 28/4885SLC6A2 31/4885
US-20260125345-A1 SALTS AND SOLID FORMS OF N-ETHYL-2-(5-FLUORO-1H-INDOL-3-YL)-N-METHYLETHAN-1-AMINE HTR1D, GRIN2D, SLC1A2 TAAR1 573/4885SLC6A4 6/4885SLC6A2 5/4885
US-20250136548-A1 FUNCTIONALIZED ALKYLAMINES BDNF, HTR2A, NTRK2 TAAR1 146/4885SLC6A4 111/4885SLC6A2 105/4885
US-20260108544-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF TAAR1 121/4885SLC6A4 26/4885SLC6A2 46/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.