Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.45 |
| ▸ | HPGD | P15428 | 13/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 13/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25276103 | 0.92 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL30254842 | 0.85 | KDM4E (0.37) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL25733481 | 0.85 | KDM4E (0.37) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL25235973 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL25733517 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL31730846 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL31730977 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL25733537 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL25230690 | 0.80 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL25274245 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250353851-A1 | PURINES AND METHODS OF THEIR USE | KINETA INC (US) | 2025-11-20 | — | — | US | disclosed |
| CN-119031913-A | Purine and methods of use thereof | 奇尼塔公司 | 2024-11-26 | — | — | CN | disclosed |
| EP-4444312-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250353851-A1 | PURINES AND METHODS OF THEIR USE | TDP1, TDP2, PIKFYVE | KDM4E 870/4885ALDH1A1 4617/4885HPGD 4116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.