Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 15/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 15/20 | 0.51 |
| ▸ | HPGD | P15428 | 14/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30254819 | 0.88 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL25737761 | 0.88 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL31731024 | 0.87 | ALDH1A1 (0.50) | KDM4EALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL25732827 | 0.87 | ALDH1A1 (0.50) | KDM4EALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL25232064 | 0.85 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL31730914 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL25276103 | 0.85 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL31730838 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL25733240 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL25733234 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250353851-A1 | PURINES AND METHODS OF THEIR USE | KINETA INC (US) | 2025-11-20 | — | — | US | disclosed |
| CN-119031913-A | Purine and methods of use thereof | 奇尼塔公司 | 2024-11-26 | — | — | CN | disclosed |
| EP-4444312-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250353851-A1 | PURINES AND METHODS OF THEIR USE | TDP1, TDP2, PIKFYVE | KDM4E 870/4885ALDH1A1 4617/4885HSD17B10 4278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.