SCHEMBL2523285

SCHEMBL2523285

CN(C)c1ccccc1-c1ccccc1P(C(C)(C)C)C(C)(C)C.c1ccc(P(c2ccccc2)c2ccccc2-c2ccccc2P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.34
NSD2 O96028 1/20 0.34
ALDH1A1 P00352 1/20 0.34
EGFR P00533 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CYP3A4 P08684 1/20 0.31
DRD1 P21728 2/20 0.31
HTR6 P50406 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29822698 0.89 ALDH1A1 (0.41) TDP1NSD2ALDH1A1EGFRLMNA
SCHEMBL29444117 0.89 ALDH1A1 (0.41) TDP1NSD2ALDH1A1EGFRLMNA
SCHEMBL29406125 0.89 MAPT (0.37) TDP1NSD2ALDH1A1EGFRLMNA
SCHEMBL238097 0.89 MAPT (0.37) TDP1NSD2ALDH1A1EGFRLMNA
SCHEMBL229536 0.89 ALDH1A1 (0.41) TDP1NSD2ALDH1A1EGFRLMNA
SCHEMBL1033292 0.86 ALDH1A1 (0.37) TDP1NSD2ALDH1A1EGFRLMNA
Bromide SCHEMBL1033291 0.86 ALDH1A1 (0.39) TDP1NSD2ALDH1A1EGFRLMNA
SCHEMBL29513054 0.76 MAPT (0.50) TDP1NSD2ALDH1A1EGFRLMNA
SCHEMBL17606910 0.76 MAPT (0.50) TDP1NSD2ALDH1A1EGFRLMNA
SCHEMBL1768181 0.75 MAPT (0.49) TDP1NSD2ALDH1A1EGFRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2379573-A2 PROCESS FOR PREPARING ETHYLENEDIALKYLPHOSPHINIC ACIDS, ESTERS AND SALTS BY MEANS OF ACETYLENE AND USE THEREOF Clariant Finance (BVI) Limited (VG) 2011-10-26 EP disclosed
WO-2010069545-A2 PROCESS FOR PREPARING ETHYLENEDIALKYLPHOSPHINIC ACIDS, ESTERS AND SALTS BY MEANS OF ACETYLENE AND USE THEREOF CLARIANT INTERNATIONAL LTD (CH) 2010-06-24 WO disclosed