Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ILK | Q13418 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30457719 | 1.00 | CFTR (0.49) | CFTRKDM4EMAPTKMT2ANPC1 | |
| SCHEMBL25280362 | 0.80 | GAA (0.40) | MAPTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30457771 | 0.80 | GAA (0.40) | MAPTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25234075 | 0.76 | HTT (0.50) | KDM4EMAPTKMT2ANPC1RAB9A | |
| SCHEMBL30458112 | 0.76 | HTT (0.50) | KDM4EMAPTKMT2ANPC1RAB9A | |
| SCHEMBL25284930 | 0.74 | KDM4E (0.40) | CFTRKDM4EMAPTKMT2ANPC1 | |
| SCHEMBL30457738 | 0.74 | KDM4E (0.40) | CFTRKDM4EMAPTKMT2ANPC1 | |
| SCHEMBL30457904 | 0.73 | GRM4 (0.47) | KDM4EMAPTKMT2ANPC1RAB9A | |
| SCHEMBL25285461 | 0.73 | GRM4 (0.47) | KDM4EMAPTKMT2ANPC1RAB9A | |
| SCHEMBL16047215 | 0.72 | HPGD (0.41) | CFTRKDM4EMAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114822-A1 | BENZOTHIAZOLE, BENZOISOXAZOLE AND BENZODIOXOLE ANALOGS AS RXFP1 RECEPTOR AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-06-22 | — | — | WO | disclosed |