Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25284930 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1NOTUMLMNAHTT | |
| SCHEMBL30458112 | 0.76 | HTT (0.50) | KDM4EALDH1A1NOTUMLMNAHTT | |
| SCHEMBL25234075 | 0.76 | HTT (0.50) | KDM4EALDH1A1NOTUMLMNAHTT | |
| SCHEMBL25233286 | 0.74 | CFTR (0.49) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL30457719 | 0.74 | CFTR (0.49) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL20839800 | 0.69 | MAPT (0.46) | KDM4EALDH1A1NOTUML3MBTL1MAPT | |
| SCHEMBL27901095 | 0.68 | NOTUM (0.51) | KDM4EALDH1A1NOTUMLMNAL3MBTL1 | |
| SCHEMBL23826015 | 0.67 | NOTUM (0.46) | KDM4EALDH1A1NOTUMLMNAL3MBTL1 | |
| SCHEMBL30152983 | 0.67 | CFTR (0.50) | KDM4EALDH1A1NOTUMLMNAL3MBTL1 | |
| SCHEMBL753404 | 0.67 | CFTR (0.50) | KDM4EALDH1A1NOTUMLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448500-A1 | BENZOTHIAZOLE, BENZOISOXAZOLE AND BENZODIOXOLE ANALOGS AS RXFP1 RECEPTOR AGONISTS | Bristol-Myers Squibb Company (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114822-A1 | BENZOTHIAZOLE, BENZOISOXAZOLE AND BENZODIOXOLE ANALOGS AS RXFP1 RECEPTOR AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-06-22 | — | — | WO | disclosed |